Evidence map›Paper›PMID 42857197›Full record

SynthesisFrontiers in sports and active living2026

Comparative effects of non-specific exercise therapies on adolescent idiopathic scoliosis: a systematic review and network meta-analysis.

Yaxin Guan, Zening Zhang, Shu Xie

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in sports and active living, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yaxin GuanSchool of Exercise and Health, Shanghai University of Sport, Shanghai, China.
Zening ZhangSchool of Exercise and Health, Shanghai University of Sport, Shanghai, China.
Shu XieSchool of Exercise and Health, Shanghai University of Sport, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Non-specific exercise therapies are widely used in the conservative management of adolescent idiopathic scoliosis (AIS) because of their accessibility and broad applicability. However, the comparative effectiveness of different non-specific exercise modalities remains unclear. This study aimed to systematically review the available evidence and compare the effects of different non-specific exercise therapies on AIS using network meta-analysis. Methods: PubMed, Embase, Web of Science, the Cochrane Library, CNKI, Wanfang, and VIP databases were searched from inception to September 2025. Eligible studies included participants diagnosed with AIS aged 10-19 years. Non-specific exercise therapy was defined as an exercise-based intervention that was not individualized according to curve type or formal three-dimensional scoliosis classification and did not involve scoliosis-specific correction principles. The primary outcome was Cobb angle. Pairwise meta-analysis was conducted using RevMan 5.4, and network meta-analysis was conducted using Stata 18.0. Treatment rankings were estimated using SUCRA values. Results: The overall pairwise random-effects meta-analysis suggested that non-specific exercise therapies were associated with a greater reduction in Cobb angle than control conditions (MD = -5.28, 95% CI -9.25 to -1.30). However, substantial heterogeneity was observed across studies (I Conclusion: Non-specific exercise therapies may be associated with reductions in Cobb angle in adolescents with idiopathic scoliosis. Spinal flexibility training and core muscle group training appeared to rank higher in the primary network analysis, but the certainty of these findings is limited by substantial heterogeneity, small sample sizes, sparse network structure, methodological limitations, concerns regarding transitivity, and the inclusion of non-randomized studies. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251242017, PROSPERO: CRD420251242017.

Indexed as

adolescent idiopathic scoliosisCobb anglecore muscle group trainingnetwork meta-analysisnon-specific exercise therapy

Identifiers

PMID42857197
PMCPMC13650006

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.