Evidence map›Paper›PMID 42857189›Full record

ArticleCureus2026

A Rare Event Causing Blindness in an Unrecognised Pregnancy: A Case Report.

Fang Ying Lim, Norshamsiah Md Din, Nurul Huda Md Amin, Nor Syahira Shariffudin

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fang Ying LimDepartment of Ophthalmology, Malacca General Hospital, Melaka, MYS.
Norshamsiah Md DinDepartment of Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.
Nurul Huda Md AminDepartment of Ophthalmology, Malacca General Hospital, Melaka, MYS.
Nor Syahira ShariffudinDepartment of Ophthalmology, Malacca General Hospital, Melaka, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purtscher-like retinopathy (PLR) is a rare, non-traumatic microembolic angiopathy characteristically associated with systemic endothelial conditions, including pre-eclampsia. While PLR typically exhibits a self-limiting course with a highly favourable visual prognosis, severe cases result in permanent, treatment-refractory blindness. We present a catastrophic, atypical case of bilateral PLR in an unrecognised pregnancy without any antenatal care. A 31-year-old primigravida without prior antenatal screening presented with a three-day history of sudden, bilateral central blurry vision and was newly diagnosed with severe pre-eclampsia. On presentation, her best-corrected visual acuity was 2/60 in the right eye and 3/60 in the left eye. Fundoscopy revealed prominent bilateral optic disc swelling, a complete macular star, and generalised Purtscher flecken. Optical coherence tomography confirmed severe macular oedema accompanied by serous macular detachment. Despite timely intervention with high-dose intravenous methylprednisolone, followed by a three-week tapering course of oral prednisolone, her visual acuity remained poor at the two-month follow-up, after which the patient defaulted. This case demonstrates that the co-existence of PLR with serous macular detachment represents an unusually severe tier of blood-retinal barrier breakdown. Furthermore, it highlights that a total lack of prenatal monitoring allows gestational hypertensive vasospasm to cascade, precipitating irreversible macular ischaemia that is entirely refractory to aggressive rescue corticosteroid therapy.

Indexed as

macular ischemiaoptic disc swellingpre-eclampsiaprenatal carepurtscher-like retinopathyserous macular detachment

Identifiers

PMID42857189
PMCPMC13650282

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.