Evidence map›Paper›PMID 42857086›Full record

ArticleCureus2026

Comparative Evaluation of Dentinal Microcrack Formation Following Root Canal Preparation With Three Single-File Nickel-Titanium Systems.

Mohd Zeeshan Ahmad, Nithin Suvarna, M S Prathap, Diksha Prerna, Kunjam Sawhney, Mallika Rathee

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Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohd Zeeshan AhmadDepartment of Conservative Dentistry and Endodontics, Rama Dental College Hospital and Research Centre, Kanpur, IND.
Nithin SuvarnaDepartment of Conservative Dentistry and Endodontics, Yenepoya Dental College, Yenepoya University, Mangalore, IND.
M S PrathapDepartment of Conservative Dentistry and Endodontics, Yenepoya Dental College, Yenepoya University, Mangalore, IND.
Diksha PrernaDepartment of Conservative Dentistry and Endodontics, Rama Dental College Hospital and Research Centre, Kanpur, IND.
Kunjam SawhneyDepartment of Conservative Dentistry and Endodontics, Himachal Institute of Dental Sciences, Paonta Sahib, IND.
Mallika RatheeDepartment of Conservative Dentistry and Endodontics, Dr. Tooth Dental Studio, Gurugram, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDentinal microcracks may develop during mechanical root canal preparation, compromising the structural integrity of root-filled teeth. This study compared dentinal microcrack formation following preparation using three single-file nickel-titanium systems. MATERIALS AND

methodsThis in vitro study was conducted on 36 extracted single-rooted mandibular premolars, which were randomly allocated into three groups (n = 12): One-Shape, Flexer ONE, and HyFlex EDM. Micro-computed tomography was used to evaluate dentinal microcracks before and after instrumentation. Incomplete microcracks, complete microcracks, craze lines, and total cracks were assessed. Two-factor mixed analysis of variance with Bonferroni-adjusted post-hoc comparisons was used for statistical analysis, with significance set at p < 0.05.

resultsInstrumentation resulted in a significant increase in incomplete and complete microcracks, craze lines, and total cracks across all three groups (all p < 0.001). The between-group effect was significant for total cracks (p = 0.004), while the group × time interaction was also significant (p = 0.004). Post-hoc analysis demonstrated a significant difference in total crack formation between the One-Shape and HyFlex EDM (mean difference = 2.50, p = 0.002). Postoperatively, One-Shape showed significantly fewer total cracks than Flexer ONE (p = 0.016) and HyFlex EDM (p < 0.001), whereas the difference between Flexer ONE and HyFlex EDM was not significant (p = 1.000).

conclusionAll three single-file systems increased dentinal microcrack formation after root canal preparation. Although differences were not significant for individual crack categories, the total crack formation differed among the systems, with One-Shape demonstrating the lowest postoperative crack formation.

Indexed as

dental cracksendodonticsmicro-computed tomographynickel-titaniumroot canal preparation

Identifiers

PMID42857086
PMCPMC13651452

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.