ArticleEULAR rheumatology open2026
Patient and healthcare factors associated with treatment response in patients with hand osteoarthritis: secondary analyses from a randomised controlled, noninferiority trial.
Article in EULAR rheumatology open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
Funding
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Abstract
Objectives: This study aimed to explore patient- and healthcare-related factors associated with treatment response 6 months after receiving recommended care for hand osteoarthritis (HOA) in specialist health services. Methods: We analysed data from 340 individuals with HOA who participated in a randomised controlled trial. Participants received patient education, medication, and/or guided hand exercises. Those with thumb carpometacarpal (CMC1-OA) were also offered a thumb orthosis. Multivariable logistic regression analyses examined associations between treatment response (OMERACT-OARSI responder criteria) and patient-related variables (age, sex, severity of CMC1-OA, pain, stiffness, grip strength, hand function, and general health), and patients' experience with care (PasOpp questionnaire). Results: Eighty percent of participants were women, and the mean age was 63.6 years. After 6 months, 96 participants (28%) were classified as OMERACT-OARSI responders. Less severe CMC1-OA (Kellgren-Lawrence grade <2) was associated with nearly doubled odds of being a responder (odds ratio [OR] 1.95, 95% CI: 1.07-3.55). Higher baseline pain intensity also increased the likelihood of good response (OR 1.18, 95% CI: 1.05-1.33). Regarding care-related factors, high scores on 'confidence in health professionals' competence' (OR 2.09, 95% CI: 1.10-3.96) and 'perceived benefit of treatment' (OR 1.74, 95% CI: 1.28-2.36) were positively associated with good response. Unexpectedly, higher scores on 'sufficient information about diagnosis and treatment' were associated with a lower probability of good response (OR 0.63, 95% CI: 0.42-0.96). Conclusions: Findings highlight the importance of early, individualized care and suggest that providing too much detailed information may unintentionally reduce patients' hope for improvement.
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