Evidence map›Paper›PMID 42856665›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Reliability and accuracy of medication-based performance measures for assessment of outpatient cardiology clinicians.

Christine Chow, Elise C Gunzburger, Chris Wilson, Taufiq S Salahuddin, Paul L Hess, Utibe R Essien, Fatima Rodriguez, Kai-Chun Yang, Boback Ziaeian, Jacob A Doll

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christine ChowDivision of Cardiology, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID 0000-0002-2117-5913
Elise C GunzburgerSection of Cardiology, Veteran Affairs Puget Sound Health Care System, Seattle, WA, USA.
Chris WilsonSection of Cardiology, Veteran Affairs Puget Sound Health Care System, Seattle, WA, USA.
Taufiq S SalahuddinSection of Cardiology, Rocky Mountain VA Medical Center, Aurora, CO; Division of Cardiology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0002-7482-2280
Paul L HessSection of Cardiology, Rocky Mountain VA Medical Center, Aurora, CO; Division of Cardiology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0002-3022-764X
Utibe R EssienDivision of General Internal Medicine & Health Services Research, David Geffen School of Medicine at the University of California Los Angeles; VA Center for the Study of Healthcare Innovation, Implementation, and Policy, Greater Los Angeles VA, Los Angeles, CA.
Fatima RodriguezDivision of Cardiovascular Medicine and the Center for Digital Health, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-5226-0723
Kai-Chun YangDivision of Cardiology, Department of Medicine, University of Washington, Seattle, WA, USA.
Boback ZiaeianDivision of General Internal Medicine & Health Services Research, David Geffen School of Medicine at the University of California Los Angeles; VA Center for the Study of Healthcare Innovation, Implementation, and Policy, Greater Los Angeles VA, Los Angeles, CA.
Jacob A DollDivision of Cardiology, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID 0000-0002-1459-0262

Funding

Opportunistic Atherosclerotic Cardiovascular Disease Risk Estimation at Abdominal CTs with Robust and Unbiased Deep LearningR01HL167974 · NHLBI · STANFORD UNIVERSITY · PI Imon Banerjee, Akshay Chaudhari · 2023 to 2026
$2.4M
Novel Incidental Calcium Evaluation (NICE)R01HL169345 · NHLBI · STANFORD UNIVERSITY · PI Imon Banerjee, Akshay Chaudhari · 2024 to 2026
$2.1M
Adherence Determinants in the Health Electronic Record Evaluation of Statins (ADHERES)R01HL168188 · NHLBI · STANFORD UNIVERSITY · PI Fatima Rodriguez · 2024 to 2026
$2.1M
HSRD VA I01 HX003570HSRD VA I01 HX003653HSRD VA IK2 HX002621NHLBI NIH HHS R01 HL167974NHLBI NIH HHS R01 HL168188NHLBI NIH HHS R01 HL169345
6 · The paper itself

Abstract

Background: Multiple performance measures are used to assess the management of common cardiovascular conditions, such as coronary artery disease (CAD), heart failure with reduced ejection fraction (HFrEF), and atrial fibrillation (AF). These measures are sometimes used to assess individual clinicians, despite lack of evidence of reliability and accuracy. We used national Veteran Affairs (VA) data to test medication-based performance measures for assessment of clinician performance in outpatient cardiology care. Methods: This retrospective study examined VA cardiology clinician/Veteran dyads from 2017-2023 to evaluate 10 medication-based performance measures for CAD, HFrEF, or AF with elevated stroke risk. Achievement of each performance measure was defined as an active prescription of an indicated medication for each eligible patient encounter, summarized at the clinician level. Reliability was calculated using the beta-binomial method. A Bayesian causal model was used to assess the impact of case complexity on performance measure achievement. Finally, we performed peer review of a subset of cases (n = 952) to assess the accuracy of three representative performance measures. Results: Of 456,071 unique cardiology encounters included in this study, 312,331 included CAD, 224,599 included HFrEF, and 178,678 included AF. These patients were treated by 1,043 cardiology clinicians. Median performance measure achievement ranged from 0.23 (SGLT2i for HFrEF) to 0.99 (beta blocker for HFrEF). Measure reliability varied from 0.63 to 0.90. Case complexity did not significantly affect performance measure achievement. Using peer review as the gold standard, accuracy was poor to moderate (balanced accuracy 0.51-0.73), and measures underestimated performance relative to peer review. Conclusions: Ten medication-based performance measures for CAD, HFrEF, and AF can be efficiently measured using electronic health record data, and most have sufficient reliability to support clinician benchmarking and the identification of potential care gaps without need for risk adjustment. However, suboptimal accuracy compared with a peer review gold standard indicates that these measures may be insufficient as a standalone assessment of clinician quality.

Indexed as

atrial fibrillationcoronary artery diseaseheart failuremedication-based measuresoutpatient cardiologyperformance measurequality of care

Identifiers

PMID42856665
PMCPMC13648801

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.