Evidence map›Paper›PMID 42856647›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Alterations in relative perfusion and synaptic patterns in Parkinson's disease using dynamic SV2A PET.

Praveen Honhar, Sule Tinaz, Faranak Ebrahimian Sadabad, Jean-Dominique Gallezot, Mika Naganawa, Mark Dias, Yunpeng Ye, Hong Gao, Nabeel Nabulsi, Yiyun Huang and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Praveen HonharDepartment of Biomedical Engineering, Yale School of Engineering and Applied Sciences, Yale University, New Haven, CT, USA.ORCID 0000-0001-9073-6270
Sule TinazDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0003-2220-8278
Faranak Ebrahimian SadabadRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Jean-Dominique GallezotRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Mika NaganawaRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Mark DiasRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Yunpeng YeRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Hong GaoRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Nabeel NabulsiRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Yiyun HuangRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Sophie E HolmesDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.
Robert A ComleyAbbVie, North Chicago, IL, USA.
Ansel T HillmerDepartment of Biomedical Engineering, Yale School of Engineering and Applied Sciences, Yale University, New Haven, CT, USA.
Sjoerd J FinnemaAbbVie, North Chicago, IL, USA.
David MatuskeyRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Richard E CarsonDepartment of Biomedical Engineering, Yale School of Engineering and Applied Sciences, Yale University, New Haven, CT, USA.

Funding

In vivo synaptic and dopamine transporter imaging in Parkinson's diseaseR01NS124819 · NINDS · YALE UNIVERSITY · PI DAVID A MATUSKEY · 2022 to 2026
$2.7M
NINDS NIH HHS R01 NS124819
6 · The paper itself

Abstract

Purpose: Dynamic [ Methods: Binding potential ( Results: PDRP was identified from Conclusions: Combining synaptic and perfusion outcomes for [

Identifiers

PMID42856647
PMCPMC13648810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.