ArticleCirculation reports2026
Prognostic Impact of In-Hospital Emergency in Patients Admitted for Non-Surgical Intensive Care.
Article in Circulation reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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12 authors.
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Abstract
Background: We aimed to elucidate the prognostic impact of in-hospital emergencies among patients who require non-surgical intensive care. Methods and Results: In total, 4,483 patients requiring non-surgical intensive care from 2011 to 2021 were included. Patient backgrounds, in-hospital management, and prognoses were compared among 4 groups according to the hospitalization route: walk-ins (group A; n=636); ambulance (group B; n=2,748); helicopter/car-based emergency medical service (group C; n=565); and in-hospital emergencies (group D; n=534). The proportion of patients admitted to the intensive care unit after in-hospital emergencies was 38.0% among those with sepsis and 29.7% among those with other non-cardiovascular diseases. Furthermore, acute heart failure (AHF), sepsis and other non-cardiovascular disease were the most common diseases in patients with in-hospital emergencies (24.3%, 23.2% and 21.5%, respectively). Kaplan-Meier curve analysis revealed that the prognosis (365-day all-cause mortality) was significantly poorer in group D than in the other groups. A multivariable Cox regression model identified group D as an independent predictor of 365-day all-cause mortality (hazard ratio 1.227; 95% confidence interval 1.027-1.467) relative to out-of-hospital admissions, especially in AHF and non-cardiovascular disease. Conclusions: Patients who required non-surgical intensive care after in-hospital emergencies mainly have AHF and non-cardiovascular etiologies such as sepsis. In-hospital emergency was identified as a significant factor associated with a higher 365-day mortality rate. A clinical approach to reduce their mortality is urgently needed.
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