Evidence map›Paper›PMID 42856566›Full record

ArticleFrontiers in pharmacology2026

Interaction of major monoterpenes from

Carolina Valle, Kerim Segura, Pilar Cárdenas, Nelson Osses, Jaime Mella, Patricio Iturriaga-Vásquez, José A Pino, Michel Lapier

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carolina ValleEscuela de Química y Farmacia, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso, Chile.
Kerim SeguraLaboratorio de Farmacología Molecular y Química Medicinal, Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería y Ciencias, Universidad de La Frontera, Temuco, Chile.
Pilar CárdenasInstituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
Nelson OssesInstituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
Jaime MellaInstituto de Química, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.
Patricio Iturriaga-VásquezLaboratorio de Farmacología Molecular y Química Medicinal, Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería y Ciencias, Universidad de La Frontera, Temuco, Chile.
José A PinoLaboratorio de Bioquímica y Farmacología Molecular, Departamento de Ciencias Biomédicas, Facultad de Ciencias de La Vida, Universidad Viña del Mar, Viña del Mar, Chile.
Michel LapierEscuela de Química y Farmacia, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major depressive disorder remains a leading cause of disability worldwide, and current antidepressants are limited by delayed therapeutic onset, incomplete efficacy, and adverse effects. Although

Indexed as

1,8-cineolecamphormolecular dockingrosemary essential oilserotonin transporterSERT functionα-pinene

Identifiers

PMID42856566
PMCPMC13649458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.