Evidence map›Paper›PMID 42856535›Full record

ArticlebioRxiv : the preprint server for biology2026

Protective near-germline antibodies to malaria elicited by RTS,S/AS01

Emma Bloch, Fiona Devys, Fabien Cannac, Monika Jain, Katrina Broadbent, Carla Sánchez, Wen-Hsin Lee, Chenjerai Jairoce, Pedro Aide, Joseph J Campo and 8 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Emma BlochISGlobal, Barcelona, Spain.ORCID 0009-0002-2227-9164
Fiona DevysInstitut Pasteur, INSERM, Université Paris Cité, Malaria Infection and Immunity, U1347 Parasitinnov, BioSPC, F-75015, Paris, France.
Fabien CannacDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Monika JainDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Katrina BroadbentProtein Technologies Unit, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Carla SánchezISGlobal, Barcelona, Spain.
Wen-Hsin LeeDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Chenjerai JairoceCentro de Investigação em Saúde de Manhiça (CISM), Mozambique.
Pedro AideCentro de Investigação em Saúde de Manhiça (CISM), Mozambique.
Joseph J CampoISGlobal, Barcelona, Spain.
Dídac MaciàISGlobal, Barcelona, Spain.
Carlo CarolisProtein Technologies Unit, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0003-4240-1139
Ian A WilsonDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Andrew B WardDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.ORCID 0000-0001-7153-3769
Rogerio AminoInstitut Pasteur, INSERM, Université Paris Cité, Malaria Infection and Immunity, U1347 Parasitinnov, BioSPC, F-75015, Paris, France.
Gemma MoncunillISGlobal, Barcelona, Spain.
Carlota DobañoISGlobal, Barcelona, Spain.
Luis M Molinos-AlbertISGlobal, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is a leading cause of childhood mortality, yet infant immune responses to vaccination remain poorly understood. Here, we characterize 88 monoclonal antibodies (mAbs) directed against the

Identifiers

PMID42856535
PMCPMC13648702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.