SynthesisFrontiers in neurology2026
Non-pharmacological interventions for cognitive function improvement in patients with Alzheimer's disease: a best evidence summary.
Synthesis in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to systematically retrieve, analyze, and synthesize evidence on non-pharmacological interventions to improve overall cognitive function in patients with Alzheimer's disease (AD), providing evidence-based references for selecting and optimizing these interventions. Methods: This review followed the PRISMA-ScR guidelines and the JBI scoping review framework. The evidence-based question was developed using the PIPOST framework. Databases and professional platforms were systematically searched from inception to January 30, 2026, using the "5S" model. Included studies were quality-appraised; eligible evidence was extracted, synthesized, graded, and assigned recommendation levels. Results: Following a strict literature screening strategy, a total of 15 studies were included, comprising 1 guideline, 7 expert consensus reports, 6 systematic reviews, and 1 randomized controlled trial. A total of 18 best evidence items were summarized and categorized into six dimensions: cognitive training (CT) and digital therapy, neuromodulation techniques, exercise interventions, lifestyle and reminiscence therapy interventions, music and sensory stimulation, and acupuncture and combined interventions. Conclusions: This study consolidated the best evidence on non-pharmacological interventions to improve overall cognitive function in patients with Alzheimer's disease, providing references for clinical practice. Clinical healthcare professionals should select appropriate interventions based on the actual clinical scenarios and individual patient conditions, and strengthen quality control during implementation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.