Evidence map›Paper›PMID 42856512›Full record

ArticleFrontiers in medicine2026

Explainable deep learning reveals a stagewise temporal deterioration from skin tone to contour to texture in Chinese women's skin aging.

Guo-Long Dong, Fan Hu, Ya-Wen Liu, Wei-Zhen Xiao, Fan Yi, Chen-Juan Zhang, Rui-Min Liu, Yue Wu

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Guo-Long Dong *School of Light Industry and Chemical Engineering, Beijing Technology and Business University, Beijing, China.
Fan Hu *Corporate R&D Department, Shanghai Pechoin Daily Chemical Co., Ltd., Shanghai, China.
Ya-Wen LiuSchool of Light Industry and Chemical Engineering, Beijing Technology and Business University, Beijing, China.
Wei-Zhen XiaoSchool of Light Industry and Chemical Engineering, Beijing Technology and Business University, Beijing, China.
Fan YiSchool of Light Industry and Chemical Engineering, Beijing Technology and Business University, Beijing, China.
Chen-Juan ZhangCorporate R&D Department, Shanghai Pechoin Daily Chemical Co., Ltd., Shanghai, China.
Rui-Min LiuCorporate R&D Department, Shanghai Pechoin Daily Chemical Co., Ltd., Shanghai, China.
Yue WuSchool of Light Industry and Chemical Engineering, Beijing Technology and Business University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin aging is a continuous and progressive physiological process characterized by gradual structural and functional changes. Early identification and accurate assessment of aging-related facial features are essential for developing targeted skincare strategies. This study aimed to establish a deep learning-based framework combined with Shapley Additive Explanations (SHAP) analysis to classify facial aging stages in Chinese women and provide interpretable evidence for personalized skincare. A total of 300 Chinese women aged 18-60 years were included. Standardized facial images were acquired using the VISIA imaging system. Four dimensions, including tone, contour, texture, and porphyrin, were evaluated, and 23 facial indicators were extracted. A hybrid multimodal deep learning classification model was developed by integrating facial image data with quantitative facial aging indicators. Five-fold stratified cross-validation was performed to evaluate model performance, with Top-2 accuracy used as the primary evaluation metric. SHAP analysis was further applied to assess the contribution weights of different facial aging indicators to model predictions. Based on the fitted quantitative facial aging indicators, a six-class facial aging classification model was established. The model demonstrated stable convergence and achieved a highest validation Top-2 accuracy of 85.0%. The confusion matrix showed that classification errors occurred primarily between adjacent aging stages. SHAP analysis revealed a progressive aging pattern characterized by early changes in skin color, middle-stage changes in facial contour, and later deterioration in skin texture. This study demonstrates that integrating deep learning with SHAP analysis can effectively classify facial aging stages in Chinese women while providing interpretable insights into the key features driving aging-related predictions.

Indexed as

aging stage classificationfacial imagingmultimodal deep learningshapley additive explanationsskin aging

Identifiers

PMID42856512
PMCPMC13649388

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.