Evidence map›Paper›PMID 42856469›Full record

ArticlebioRxiv : the preprint server for biology2026

Deconstruction of

Nilima Walunjkar, James H Miller, Lydia Levesque, Justin C Fay

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nilima WalunjkarDepartment of Biology, University of Rochester, Rochester, NY 14627.ORCID 0009-0005-3709-7103
James H MillerDepartment of Biology, University of Rochester, Rochester, NY 14627.ORCID 0009-0005-9597-1604
Lydia LevesqueDepartment of Biology, University of Rochester, Rochester, NY 14627.
Justin C FayDepartment of Biology, University of Rochester, Rochester, NY 14627.ORCID 0000-0003-1893-877X

Funding

Genetic basis and evolution of thermotolerance in the Saccharomyces yeast speciesR01GM080669 · NIGMS · WASHINGTON UNIVERSITY · PI FAY, JUSTIN C · 2007 to 2025
$5.3M
Genetic constraints on adaptive evolutionR35GM156247 · NIGMS · UNIVERSITY OF ROCHESTER · PI Justin C Fay · 2025 to 2026
$617k
NIGMS NIH HHS R01 GM080669NIGMS NIH HHS R35 GM156247
6 · The paper itself

Abstract

The genetic basis of phenotypic differences between species is fundamental to our view of evolution. In contrast to variation within species, phenotypic differences between species can result from a long-term sequential process whereby prior steps and multiple changes at a single locus can play important roles. However, investigating the genetic basis of phenotypes that have evolved over long time periods is limited by reproductive barriers between species. In this study, we use hybrid genetic analysis to examine reproductively isolated

Identifiers

PMID42856469
PMCPMC13648620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.