In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Daniel A SnellingsDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0003-0615-9111 Kow EssumanDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-6781-7248 Benjamin FinanderDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-8095-6066 Eitan GoodmanDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0009-0004-8461-6407 Christie CambridgeDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0009-0006-4722-090X Jannis BueckingDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0009-0003-8784-1071 Brian ChhoukDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0009-0009-9916-9597 Urmi GhoshDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0009-0005-6161-1459 Michael B MillerDivision of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-6205-3314 Christopher A WalshDivision of Genetics and Genomics and Manton Center for Orphan Disease Research, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-0156-2238 Funding
Cell Identity Determination In Human Brain: Somatic Mutation and Cell LineageR01NS032457 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI Alice Eunjung Lee, Christopher A. Walsh · 1995 to 2026
$12.7MGenetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4MIlluminating neurodegenerative tauopathy from somatic genomic landscapes of single human brain cellsDP2AG086138 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Michael B Miller · 2023 to 2026
$2.7MMechanisms of Somatic Mutation in Alzheimer's Disease Using Single Neuron AnalysisR01AG082346 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Michael B Miller · 2024 to 2026
$2.7MDevelopment of an Efficient High Throughput Technique for the Identification of High-Impact Non-Coding Somatic Variants Across Multiple Tissue TypesUH3NS132138 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI Peter J Park, Christopher A. Walsh · 2025 to 2026
$1.4MInvestigating the Role of Somatic Mutations in Neurofibromatosis BrainF32NS133029 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI SNELLINGS, DANIEL · 2023 to 2024
$144kNIA NIH HHS DP2 AG086138NIA NIH HHS R01 AG082346NICHD NIH HHS P50 HD105351NINDS NIH HHS F32 NS133029NINDS NIH HHS R01 NS032457NINDS NIH HHS UH3 NS132138
6 · The paper itselfAbstract
Tumorigenesis is a multi-step process shaped by the accumulation of somatic driver mutations, but identifying the earliest steps and cell of origin of tumorigenesis remains challenging. Single cell genomics in >1.7 million single cells across donors with the cancer predisposition syndrome neurofibromatosis type 1 (NF-1), shows that somatic 'second-hit' mutations in
Identifiers
PMID42856403
PMCPMC13648584
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