Evidence map›Paper›PMID 42855946›Full record

ArticleChemistry & biodiversity2026

UHPLC/MS-MS Profiling, Antioxidant and Antimicrobial Properties of Atriplex halimus L. and Marrubium deserti De Noé Extracts: In Vitro and In Silico.

Nacira Siad, Chahrazed Hamia, Amar Djeridane, Mohamed Benalia, Reguia Mahfoudi, Hicham Bouakkaz, Mustafa Abdullah Yilmaz, Oguz Cakir, Abbas Tarhan, Mohamed Yousfi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nacira SiadLaboratoire Des Sciences Fondamentales, Amar Telidji University, Laghouat, Algeria.ORCID https://orcid.org/0009-0002-9251-0472
Chahrazed HamiaLaboratoire Des Sciences Fondamentales, Amar Telidji University, Laghouat, Algeria.ORCID https://orcid.org/0009-0002-2324-6153
Amar DjeridaneLaboratoire Des Sciences Fondamentales, Amar Telidji University, Laghouat, Algeria.ORCID https://orcid.org/0000-0003-3416-118X
Mohamed BenaliaLaboratoire Des Sciences Fondamentales, Amar Telidji University, Laghouat, Algeria.
Reguia MahfoudiLaboratoire Des Sciences Fondamentales, Amar Telidji University, Laghouat, Algeria.
Hicham BouakkazLaboratoire Des Sciences Fondamentales, Amar Telidji University, Laghouat, Algeria.
Mustafa Abdullah YilmazScience and Technology Research and Application Center, Dicle University, Diyarbakir, Türkiye.ORCID https://orcid.org/0000-0002-4090-7227
Oguz CakirScience and Technology Research and Application Center, Dicle University, Diyarbakir, Türkiye.ORCID https://orcid.org/0000-0002-8006-2054
Abbas TarhanScience and Technology Research and Application Center, Dicle University, Diyarbakir, Türkiye.ORCID https://orcid.org/0000-0001-5196-3892
Mohamed YousfiLaboratoire Des Sciences Fondamentales, Amar Telidji University, Laghouat, Algeria.ORCID https://orcid.org/0000-0003-3947-9867

Funding

Amar Telidji University
6 · The paper itself

Abstract

This study aims to evaluate the chemical composition and both in vitro and in silico antioxidant and antimicrobial activities of Atriplex halimus L. and Marrubium deserti De Noé, collected from Algeria. UHPLC‑MS/MS analysis revealed that the major compounds in the tested extracts are protocatechuic aldehyde, caffeic acid, cynaroside, and cosmosiin. The data demonstrated that the dichloromethane fraction was richer in polyphenols and flavonoids than the aqueous fraction. The extracts exhibited greater antioxidant capacity against ABTS compared to DPPH and FRAP assays. Antimicrobial activity was assessed by determining MIC

Indexed as

Anti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsAntioxidantsAtriplexMarrubiumPlant ExtractsBenzothiazolesBiphenyl CompoundsChromatography, High Pressure LiquidMicrobial Sensitivity TestsPicratesTandem Mass Spectrometry1,1-diphenyl-2-picrylhydrazylAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsAntioxidantsBenzothiazolesBiphenyl CompoundsPicratesPlant Extractsantimicrobial capacityantioxidant activityAtriplex halimus L.Marrubium deserti De Noémolecular dockingphenolic compounds

Identifiers

PMID42855946
PMCPMC13653120

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.