Evidence map›Paper›PMID 42855935›Full record

ArticleChemistry & biodiversity2026

Development of Benzothiophene-Bearing Bis-oxadiazole Derivatives for Potential Anticancer Targets: Evaluation of DFT, ADME-Tox, and In Silico Docking.

Nagaraju Madala, Vishal Sharma, Srilalitha Vinnakota

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nagaraju MadalaCentre For Chemical Sciences and Technology, University College of Engineering Science and Technology Hyderabad, Jawaharlal Nehru Technological University Hyderabad, Hyderabad, Telangana, India.ORCID https://orcid.org/0009-0009-7077-5868
Vishal SharmaDiscovery Chemistry Division, Jubilant Biosys Ltd, Knowledge Park II, Greater Noida, Uttar Pradesh, India.
Srilalitha VinnakotaDepartment of Chemistry, Faculty of Science and Technology, ICFAI Foundation for Higher Education, Hyderabad, Telangana, India.

Funding

Researches on higher education program VSNCUP2024001
6 · The paper itself

Abstract

Combining two pharmacophores into one molecule with multiple applications presents interest in the field of medicinal chemistry. Benzo[b]thiophenes are among privileged scaffolds due to their wide biological activities, whereas oxadiazoles are versatile linkers with pharmacological potential. Thus, this article focused on the synthesis of novel benzo[b]thiophene-linked bis-oxadiazoles and the exploration of their anticancer potential. The structural elucidation of the prepared oxadiazole compounds was established by

Indexed as

Antineoplastic AgentsDensity Functional TheoryMolecular Docking SimulationOxadiazolesThiophenesCaco-2 CellsCell Line, TumorCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsbenzothiopheneOxadiazolesThiophenesADMET lab 3.0anticancerbenzothiopheneBis‐oxadiazoleDFTin silico techniques

Identifiers

PMID42855935
PMCPMC13653123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.