Evidence map›Paper›PMID 42855896›Full record

ArticleChemistry & biodiversity2026

Chemometric-Assisted Extraction Optimization and HPLC-MS Profiling of Mentha × villosa Targeting Photoprotective Activity.

Juliana de Medeiros Gomes, Thalisson Amorim de Souza, Márcio Vinícius Cahino Terto, Maria Beatriz Félix Mendes Nunes, Hariel Maffei Umesaki Tessaro, Joanda Paolla Raimundo E Silva, Samuel Paulo Cibulski, Luiz Alberto Lira Soares, Vera Isaac, Marcelo Sobral da Silva and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juliana de Medeiros GomesLaboratório Multiusuário de Caracterização e Análise (LMCA), Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil.
Thalisson Amorim de SouzaLaboratório Multiusuário de Caracterização e Análise (LMCA), Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil.
Márcio Vinícius Cahino TertoLaboratório Multiusuário de Caracterização e Análise (LMCA), Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil.
Maria Beatriz Félix Mendes NunesLaboratório Multiusuário de Caracterização e Análise (LMCA), Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0002-3802-8514
Hariel Maffei Umesaki TessaroLaboratório De Cosmetologia, Faculdade De Ciências Farmacêuticas, Universidade Estadual Paulista, Araraquara, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-3400-4347
Joanda Paolla Raimundo E SilvaDepartamento De Farmácia, Universidade Estadual de Maringá, Maringá, Paraná, Brazil.
Samuel Paulo CibulskiFaculdade De Ciências da Saúde do Trairi, Universidade Federal do Rio Grande Do Norte, Santa Cruz, Rio Grande do Norte, Brazil.ORCID https://orcid.org/0000-0003-0503-8692
Luiz Alberto Lira SoaresNúcleo De Desenvolvimento Analítico e Tecnológico de Fitoterápicos, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.ORCID https://orcid.org/0000-0002-3142-6173
Vera IsaacLaboratório De Cosmetologia, Faculdade De Ciências Farmacêuticas, Universidade Estadual Paulista, Araraquara, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-7402-920X
Marcelo Sobral da SilvaLaboratório Multiusuário de Caracterização e Análise (LMCA), Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil.
Josean Fechine TavaresLaboratório Multiusuário de Caracterização e Análise (LMCA), Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0003-0293-2605

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 141383/2018-6Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 152472/2024-0Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES) 001Financiadora de Estudos e Projetos (FINEP) by means of INCT-Rennofito 465536/2014-0
6 · The paper itself

Abstract

Mentha × villosa is a food and medicinal plant with long history of use. However, its use as potential ingredient for cosmetic formulations continues underexplored. Based on that, the present study sought to optimize the extraction of M. × villosa (MV-OE), characterize its composition, evaluate its antioxidant capacity and photoprotective effects alone and in combination with ethylhexyl methoxycinnamate (EHMC), a commercial sunscreen filter, in prototype formulations. Extraction was optimized through DoE, total phenolic content, and rosmarinic acid were quantified, while antioxidant activity was determined by DPPH and ABTS assays. The chemical profile of extracts was analyzed by HPLC-DAD-ESI-MS

Indexed as

AntioxidantsMenthaPlant ExtractsSunscreening AgentsBenzothiazolesBiphenyl CompoundsChromatography, High Pressure LiquidCinnamatesLiquid Chromatography-Mass SpectrometryPhenolsPicratesRosmarinic AcidSpectrometry, Mass, Electrospray IonizationSulfonic Acids1,1-diphenyl-2-picrylhydrazyl2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAntioxidantsBenzothiazolesBiphenyl CompoundsCinnamatesPhenolsPicratesPlant ExtractsRosmarinic AcidSulfonic AcidsSunscreening Agentsfactorial designLamiaceaemojito mintnatural products

Identifiers

PMID42855896
PMCPMC13653112

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.