Evidence map›Paper›PMID 42855873›Full record

ArticleThe American journal of case reports2026

Case Report: Botulinum Toxin Type A Injection for Bruxism Following Left Basal Ganglia Hemorrhage.

Jialing Wang, Xudong Zhu, Yanjie Fu, Ya Zheng

Abstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jialing WangDepartment of Geriatric Rehabilitation, Ningbo Rehabilitation Hospital, Ningbo Key Laboratory of Brain Cognitive Rehabilitation, Ningbo, Zhejiang, China.
Xudong ZhuDepartment of Equipment, Ningbo Rehabilitation Hospital, Ningbo, Zhejiang, China.
Yanjie FuDepartment of Geriatric Rehabilitation, Ningbo Rehabilitation Hospital, Ningbo Key Laboratory of Brain Cognitive Rehabilitation, Ningbo, Zhejiang, China.
Ya ZhengDepartment of Geriatric Rehabilitation, Ningbo Rehabilitation Hospital, Ningbo Key Laboratory of Brain Cognitive Rehabilitation, Ningbo, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Post‑stroke bruxism is an underrecognized complication that may impair oral function, cause orofacial pain, and negatively impact rehabilitation outcomes. Botulinum toxin type A (BoNT‑A) has been reported for bruxism, but its application in post‑stroke populations remains sparsely documented. This case describes the assessment and treatment of bruxism following cerebral hemorrhage, utilizing the Standardized Tool for the Assessment of Bruxism (STAB) as a structured multidimensional framework. CASE REPORT A 40-year-old man developed bruxism during recovery from a massive left hemispheric intracerebral hemorrhage after decompressive craniectomy and hematoma evacuation. About 3 months after admission, he began to exhibit bilateral masseter muscle hypertrophy with marked tenderness, temporomandibular joint pain, and drooling from the right mouth corner, with no prior history of bruxism. STAB-based evaluation yielded the following Axis A findings: Subject-based assessment revealed nocturnal grinding reported by caregivers. Clinically based assessment revealed bilateral masseter hypertrophy, tenderness on palpation, and dental wear. Instrument-based assessment (surface electromyography used for injection guidance) confirmed increased masseter muscle activity at rest and during clenching. Symptoms were refractory to occlusal splint therapy combined with hot compresses. At 48 hours after electromyography-guided injection into the bilateral masseter muscles (50 U per side, divided into 3 sites per side), muscle tension and tenderness were markedly reduced, and clinical improvement persisted at 6-month follow-up. CONCLUSIONS In this single case, BoNT‑A injection was temporally associated with symptom relief in post-stroke bruxism. STAB provided a structured multidimensional assessment framework. These descriptive findings have limited generalizability. Controlled studies are needed to establish the efficacy and safety of this intervention in the post‑stroke population.

Indexed as

Basal Ganglia HemorrhageBotulinum Toxins, Type ABruxismNeuromuscular AgentsAdultHumansInjections, IntramuscularMaleMasseter MuscleBotulinum Toxins, Type ANeuromuscular Agents

Identifiers

PMID42855873
PMCPMC13663907

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.