Evidence map›Paper›PMID 42855462›Full record

ArticlePediatric research2026

Community-based monitoring of neonatal jaundice using the point-of-care Bilistick® System 2.0.

Irene Lapucci, Gabriella Tambascia, Lorenzo Zucchini, Maria Teresa Calipa, Maria Vittoria Sola, Luca Ronfani, Laura Travan, Jaundice Working Group

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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Irene Lapucci *University of Trieste, Trieste, Italy.
Gabriella TambasciaItalian National Institute of Health, Rome, Italy.
Lorenzo Zucchini *Bilimetrix srl, Trieste, Italy.
Maria Teresa CalipaSan Polo Hospital, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), Monfalcone, Italy.
Maria Vittoria SolaRetired Pediatrician in Trieste, Italy; formerly at Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), Trieste, Italy.
Luca RonfaniInstitute for Maternal and Child Health - IRCCS "Burlo Garofolo" - Trieste, Trieste, Italy.
Laura TravanInstitute for Maternal and Child Health - IRCCS "Burlo Garofolo" - Trieste, Trieste, Italy. laura.travan@burlo.trieste.it.
Jaundice Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeonatal jaundice often peaks after discharge, creating the need for reliable post-discharge monitoring. This study evaluated the feasibility and safety of a hospital-to-community pathway using the Bilistick® System 2.0 within routine Community Health Family Services (CHFS).

methodsThis retrospective observational study was conducted within a Local Health Authority in northeastern Italy. Newborns eligible for out-of-hospital bilirubin testing according to a Diagnostic-Therapeutic Assistance Pathway (DTAP) were referred either to CHFS or to hospital follow-up based on bilirubin risk profile, clinical factors, and organizational considerations.

resultsOf 397 eligible newborns meeting inclusion criteria, 244 were included. Of these, 108 (44.3%) were referred to CHFS, 135 (55.3%) to hospital follow-up, and 1 was lost to follow-up. Among newborns referred to CHFS, 97 (89.8%) completed monitoring without hospital referral. Eleven were referred to the hospital, of whom 7 received phototherapy. Among newborns referred directly to the hospital, 6 (4.4%) required phototherapy. No sampling-related adverse events, missed phototherapy, exchange transfusions, or cases of kernicterus were recorded.

conclusionCommunity-based bilirubin monitoring using the Bilistick® System 2.0 appears feasible and safe for selected low-risk newborns within a structured hospital-to-community pathway. IMPACT: To our knowledge, this is the first real-world evaluation of a structured hospital-to-community pathway integrating point-of-care bilirubin testing into routine community care within UNICEF's Baby-Friendly Initiative framework. Among selected newborns referred to community services, 89.8% completed bilirubin monitoring without hospital referral. Community midwives identified infants requiring escalation of care; no missed phototherapy, exchange transfusion, or kernicterus occurred. The model may reduce unnecessary hospital reassessment and disruption to the mother-infant dyad; local administrative estimates indicate a direct cost difference of €32.30 per bilirubin reassessment.

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.