ArticleMedicine2026
Diagnostic value of hematological inflammatory indices for renal involvement in adult IgA vasculitis: A cross-sectional study.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate the diagnostic value of hematological inflammatory indices, including neutrophil-to-lymphocyte ratio (NLR), red cell distribution width (RDW), and aggregate index of systemic inflammation (AISI), for detecting renal involvement in adult patients with immunoglobulin A (IgA) vasculitis. A cross-sectional study was conducted in 67 adult patients with IgA vasculitis (IgAV) and 70 healthy controls at 103 Military Hospital, Vietnam. Compared with healthy controls, patients with IgAV showed higher white blood cell, neutrophil, and monocyte counts, as well as elevated NLR and AISI, and lower hemoglobin levels (all P < .05). Renal involvement was identified in 38.8% of patients. Those with renal involvement had significantly higher RDW, NLR, and AISI than patients without renal involvement. Receiver operating characteristic analysis showed moderate diagnostic performance, with area under the curves (AUCs) of 0.682 for NLR, 0.675 for RDW, and 0.674 for AISI. The combined RDW + NLR model improved diagnostic accuracy (AUC = 0.759, 95% CI: 0.636-0.882), while the RDW + AISI model showed the best performance (AUC = 0.797, 95% CI: 0.684-0.911), with sensitivity of 53.8% and specificity of 95.1% (P < .001). Univariate analysis showed that elevated RDW, NLR, and AISI were significantly associated with renal involvement. Multivariate logistic regression adjusted for age and sex confirmed these indices as independent predictors. RDW, NLR, and AISI are independently associated with renal involvement in adult IgAV. The combination of RDW and AISI demonstrated the highest diagnostic performance and may serve as a simple, cost-effective tool for identifying patients at increased risk of renal involvement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.