ArticleMedicine2026
Global trends and hotspots of Charcot-Marie-Tooth disease: A bibliometric analysis.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
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Authors and funding
4 authors.
Funding
Abstract
backgroundCharcot-Marie-Tooth disease (CMT) is a hereditary neuropathy characterized by progressive sensory and motor deficits. Over the past decade, the volume of CMT-related publications has increased steadily. This study aimed to examine global publication trends, key contributors, collaborative networks, and emerging research hotspots in CMT through bibliometric analysis.
methodsPublications related to CMT from 2014 to 2024 were retrieved from the Web of Science Core Collection. VOSviewer 1.6.20, CiteSpace 6.3.R1, and the R package "bibliometrix" were used to analyze annual publication output, country and institutional contributions, journal distribution, author collaboration, citation networks, keyword co-occurrence, and research trends.
resultsA total of 1531 CMT-related articles were identified, with an annual growth rate of 1.75%. The average number of citations per document was 15.56. The United States ranked first in research output, contributing 324 publications and accounting for 21.2% of the total, followed by China and Italy. The University of London and University College London were the leading institutions, and the Journal of the Peripheral Nervous System and Neuromuscular Disorders were the main publication venues. Keyword analysis showed that "mutations," "neuropathy," and "gene" were the most frequent terms, reflecting sustained attention to genetic mechanisms, disease pathogenesis, and molecular diagnosis. Citation burst analysis identified "variants" and "deoxyribonucleic acid (DNA) methylation" as recent burst keywords beginning in 2022, suggesting increasing interest in variant interpretation, epigenetic regulation, and advanced sequencing-based approaches, including whole-genome sequencing.
conclusionThis bibliometric analysis shows that global CMT research maintained steady growth from 2014 to 2024, with the United States, China, Italy, the United Kingdom, and several leading institutions making major contributions. Current research remains centered on genetic mechanisms and molecular diagnosis, while recent hotspots indicate a shift toward variant interpretation, epigenetic regulation, whole-genome sequencing, and personalized medicine. Future bibliometric studies should include additional databases and underrepresented regions to provide a more comprehensive understanding of the evolving CMT research landscape.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.