Evidence map›Paper›PMID 42853936›Full record

ArticleScience advances2026

Phage-ICE tandems facilitate bacterial adaptation and antimicrobial resistance spread.

Jinhu Huang, Jiaqi Zhao, Pengchao Zhan, Xingyang Dai, Xinming Pan, Zhenmiao Li, Wenbin Zhao, Xiaoli Shi, Xiaoming Wang, Shengyong Mao and 3 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jinhu HuangSanya Institute of Nanjing Agricultural University, Sanya 572025, China.ORCID 0000-0001-8149-1486
Jiaqi ZhaoMOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0009-0007-1868-4171
Pengchao ZhanLaboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, National Center for International Research on Animal Gut Nutrition, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Xingyang DaiMOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0001-6873-9678
Xinming PanWOAH Reference Lab for Swine Streptococcosis, Nanjing 210095, China.
Zhenmiao LiThe Air Force Hospital of Eastern Theater of PLA, Nanjing 210002, China.
Wenbin ZhaoSanya Institute of Nanjing Agricultural University, Sanya 572025, China.
Xiaoli ShiNational Experimental Teaching Demonstration Center for Animal Science, Nanjing 210095, China.
Xiaoming WangMOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Shengyong MaoLaboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, National Center for International Research on Animal Gut Nutrition, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-0089-9314
Jiale MaWOAH Reference Lab for Swine Streptococcosis, Nanjing 210095, China.ORCID 0000-0002-2163-9247
Liping WangMOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0003-4648-8155
Jinxin LiuSanya Institute of Nanjing Agricultural University, Sanya 572025, China.ORCID 0000-0002-5302-866X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phages and integrative and conjugative elements (ICEs) drive bacterial evolution, but how their interplay shapes bacterial adaptation and antimicrobial resistance (AMR) dissemination remains unclear. Here, we characterize phage-ICE tandems formed by site-specific accretion of phages and ICEs into cotransferable units. In

Indexed as

Adaptation, PhysiologicalBacteriaBacteriophagesDrug Resistance, BacterialAnti-Bacterial AgentsConjugation, GeneticAnti-Bacterial Agents

Identifiers

PMID42853936
PMCPMC13651849

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.