In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Lucile FossierDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-1837-9093 Marc YehyaDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0000-0003-4098-5580 Sri Karthika ShanmugamDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-1467-401X Ryan MahlingDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-4590-2724 Timothy ChoDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0009-0002-5809-548X Audrey KochissDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0009-0007-4800-9855 Allen L HsuDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0000-0003-2065-3802 Sandra B GabelliDiscovery Chemistry, Merck Research Laboratory, Merck and Co. Inc., West Point, PA 19486, USA.ORCID 0000-0003-1205-5204 Gordana Vunjak-NovakovicDepartment of Biomedical Engineering, Columbia University, New York, NY 10027, USA.ORCID 0000-0002-9382-1574 Henry M ColecraftDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-2340-8899 Manu Ben-JohnyDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-5645-0815 Funding
Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3MTissue Engineering Resource Center: TTDP41EB027062 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Gordana Vunjak-Novakovic · 2019 to 2026
$12.6MStructure-Function of Calcium Channel Complexes in Cardiac Physiology and DiseaseP01HL164319 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Manu Ben Johny · 2023 to 2026
$12.1MEngineering Vascularized Cardiac MuscleR01HL076485 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Gordana Vunjak-Novakovic · 2005 to 2026
$9.2MMechanism-inspired Strategies to Prevent Pathogenic Late Na Current in Cardiac ArrhythmiasR01HL163576 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Manu Ben Johny · 2023 to 2026
$2.2MDiscerning L-type trafficking modulation by targeted excision of ubiquitin and SUMOK99HL177343 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Sri Karthika Shanmugam · 2025 to 2026
$267kNCI NIH HHS P30 CA013696NHLBI NIH HHS K99 HL177343NHLBI NIH HHS P01 HL164319NHLBI NIH HHS R01 HL076485NHLBI NIH HHS R01 HL163576NIBIB NIH HHS P41 EB027062
6 · The paper itselfAbstract
Despite their emerging prominence, ion channelopathies have remained challenging to correct, as ion channel dysfunction linked to disease is multifaceted, involving changes in activity and/or localization. Yet, current corrective strategies typically focus on restoring only one aspect leading to incomplete efficacy. Here, focusing on the voltage-gated sodium channel, Na
Indexed as
Myocytes, CardiacNAV1.5 Voltage-Gated Sodium ChannelAnimalsHumansIon Channel GatingMiceNAV1.5 Voltage-Gated Sodium ChannelSCN5A protein, human
Identifiers
PMID42853924
PMCPMC13651866
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