Evidence map›Paper›PMID 42853547›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2026

Biological Systems as Physical Data Processors: Evolution as a Case of Embodied Computing.

Víctor de Lorenzo

Abstract readReview
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Víctor de LorenzoSystems Biology Department, Centro Nacional de Biotecnología CSIC, Madrid, Spain.ORCID https://orcid.org/0000-0002-6041-2731

Funding

European Union HORIZON-CL6-2021-UE101060625
6 · The paper itself

Abstract

The prevailing view of biological evolution is not unlike bricolage/pastiche/tinkering-in sharp contrast with rational engineering. Yet, different paths often lead to solutions that coincide or converge whether they emerge from naturally-occurring evolution or rationally designed. Such a conjunction-often presented as an anecdote-reveals the ability of biological systems to explore solution spaces and gravitate toward information-rich attractors, which can be found through different routes. This scenario evokes one of embodied computing, a non-conventional type of data processing in which the solution to a problem is not delivered through numerical calculations but through its implementation in a material object. Once left to undergo a physical process the object manages a large number of parameters for reaching a multi objective optimum through thermodynamically-driven processes. The course of information is thus a physical flow and the outcome is a physical currency. The consequences of this notion for bioengineering are remarkable.

Indexed as

Biological EvolutionSystems BiologyAnimalsBioengineeringModels, BiologicalThermodynamicsadaptive laboratory evolutionevolutionary convergencefitness landscapesinformation theorymulti‐objective optimizationsynthetic biologysystems biology

Identifiers

PMID42853547
PMCPMC13651922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.