ArticleBrain structure & function2026
Receptor architecture shapes the regional organization of the macaque cingulate cortex.
Article in Brain structure & function, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The cingulate cortex plays a central role in emotion, motivation, decision-making and motor control, yet its internal organization in the macaque brain remains debated. In the present study, we examined the cyto- and receptor architectonic organization of the macaque cingulate cortex and provide a 3D parcellation of the identified areas in both surface and volumetric representations. Multivariate receptor analyses consistently separated areas of the anterior cingulate cortex (ACC) and anterior midcingulate cortex (aMCC) from those of the posterior midcingulate cortex (pMCC) and posterior cingulate cortex (PCC), supporting the definition of four principal cingulate regions in the macaque brain. These regions are characterized by distinct receptor balances: the ACC is enriched with glutamatergic and monoaminergic receptors; the aMCC exhibits high densities of modulatory receptors; the pMCC is characterized by overall lowest receptor densities; and the PCC displays intermediate receptor densities with relatively higher GABA
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