Evidence map›Paper›PMID 42853348›Full record

ReviewThe Saudi dental journal2026

Artificial intelligence in orthodontics: clinical maturity, evidence gaps, and emerging applications-a narrative review.

Kanza Chandio, Laiba Iftikhar, Anum Shehzad, Ifrah Rao, Minahil Waseem, Muhammad Anas, Muhammad Farrukh, Ammar Al Shalabi, Sameh Talaat, Sinan Sen and 2 more

Abstract readReview
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In one paragraph

Review in The Saudi dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kanza ChandioZiauddin University, Karachi, Pakistan.ORCID https://orcid.org/0009-0009-7812-6141
Laiba IftikharDow International Dental College, Karachi, Pakistan.
Anum ShehzadShaheed Zulfikar Ali Bhutto Institute of Science and Technology University, Karachi, Pakistan.ORCID https://orcid.org/0009-0002-8367-3085
Ifrah RaoRashid Latif Dental College, Lahore, Pakistan.
Minahil WaseemArmy Medical College, Rawalpindi, Pakistan.
Muhammad AnasBacha Khan Dental College, Mardan, Pakistan.ORCID https://orcid.org/0009-0005-9914-397X
Muhammad FarrukhMargalla Institute of Health Sciences, Rawalpindi, Pakistan.
Ammar Al ShalabiHamdan Bin Mohammed College of Dental Medicine (HBMCDM), Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, United Arab Emirates.
Sameh TalaatFuture University in Egypt, Cairo, Egypt.
Sinan SenUniversity Hospital Schleswig-Holstein, Kiel, Germany.ORCID http://orcid.org/0000-0001-5907-5398
Fatma HassaneinKing Salman International University, El-Tor, Egypt.ORCID https://orcid.org/0009-0000-8010-9265
Tarek ElshazlyUniversity Hospital Bonn, Bonn, Germany. tarek.m.elshazly@gmail.com.ORCID http://orcid.org/0000-0002-3219-9048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) is rapidly transforming orthodontics by enhancing diagnostic accuracy, supporting clinical decision-making, and facilitating digital workflows. This narrative review provides a comprehensive overview of current AI technologies and their applications in orthodontics, including diagnostic imaging, treatment planning, treatment monitoring, patient communication, education, and emerging generative AI tools. The available evidence indicates that automated cephalometric landmark detection and cone-beam computed tomography (CBCT) segmentation have among the most advanced technical and external-validation evidence bases in orthodontic AI, whereas digital-model analysis has demonstrated high technical performance but more limited independent validation. However, no application met the predefined criteria for higher clinical maturity because prospective clinical effectiveness remained insufficiently established. Other emerging or experimental applications include AI-assisted treatment planning, remote monitoring, large language models (LLMs), and robotic systems, for which evidence remains predominantly retrospective, technical, feasibility-based, or early clinical. However, much of the current evidence is derived from retrospective studies, technical validation investigations, and proof-of-concept reports, with limited prospective clinical data demonstrating improvements in treatment quality, efficiency, or long-term patient outcomes. Important challenges remain regarding data quality, algorithmic bias, external validation, explainability, patient privacy, and regulatory oversight. Overall, AI should currently be regarded as a clinician-supervised decision-support tool rather than a replacement for professional expertise. Future progress is likely to depend on robust prospective clinical trials, transparent reporting, and responsible integration of AI into evidence-based orthodontic practice and the broader digital transformation of dentistry.

Indexed as

Artificial intelligenceComputer-assisted diagnosisMachine learningOrthodonticsTelemedicine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.