Evidence map›Paper›PMID 42853330›Full record

ArticleArchives of orthopaedic and trauma surgery2026

Fewer poor joint awareness results with cementless TKA compared with the same-design cemented implant.

Luca De Berardinis, Filippo Leggieri, Paolo Salari, Giuseppe Polizzotti, Andrea Baldini

Abstract readComparative Study
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In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Luca De BerardinisOrthopaedic and Trauma Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Filippo LeggieriUniversity of Florence, Florence, Italy. filippo.leggieri@unifi.it.
Paolo SalariOrthopaedic Unit, Istituto Fiorentino di Cura e Assistenza, Firenze, Italy.
Giuseppe PolizzottiOrthopaedic Unit, Istituto Clinico San Rocco di Ome, Brescia, Italy.
Andrea BaldiniOrthopaedic Unit, Istituto Fiorentino di Cura e Assistenza, Firenze, Italy.ORCID https://orcid.org/0000-0002-6073-8491

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComparisons of cemented and cementless TKA have focused on mean outcomes and generally reported equivalence. We hypothesized that a 3D-printed full-titanium cementless TKA and the same-design cemented implant would not differ significantly in average joint awareness but would differ in the proportion of patients with the poorest results, and we compared the two both at the mean and across the outcome distribution.

methodsProspective two-cohort study of 109 primary unilateral TKAs (54 cementless, 55 cemented) for end-stage knee osteoarthritis, with complete 24-month follow-up. Exclusion criteria were valgus deformity and bilateral surgery. The primary outcome was the FJS-12, analysed both at the mean (multivariable linear regression, with propensity score overlap weighting as sensitivity analysis) and across its distribution (quantile regression). Secondary outcomes were PASS achievement (FJS-12 ≥ 33.3), OKS, and time to functional satisfaction.

resultsThe cementless group was younger (P < 0.001) with more men (P = 0.008). Mean FJS-12 was not different between groups after adjustment (β = 7.4, 95% CI - 1.8 to 16.6, P = 0.115), although the confidence interval did not exclude a difference exceeding the minimal clinically important difference; this finding was reproduced by overlap weighting. On quantile regression, cementless patients scored significantly higher at the 10th and 25th percentiles (adjusted P = 0.028 and 0.021) but not at the median or above. A greater proportion of cementless patients achieved the PASS (96.3% vs. 76.4%; absolute difference 19.9%, 95% CI 7.1 to 32.9; number needed to treat 5), which persisted after adjustment (P = 0.005). No significant differences were observed in OKS (P = 0.91) or time to functional satisfaction (adjusted P = 0.39). No revisions or loosening occurred.

conclusionThe 3D-printed full-titanium cementless TKA did not produce a significantly higher mean FJS-12 than the same-design cemented device at 24 months, but it significantly reduced the proportion of patients with poor joint awareness outcomes. LEVEL OF EVIDENCE: III.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisOsteoarthritis, KneeAgedBone CementsFemaleHumansMaleMiddle AgedPatient SatisfactionPrinting, Three-DimensionalProspective StudiesProsthesis DesignBone Cements3D printingCementedCementlessFull-titaniumTotal knee arthroplasty

Identifiers

PMID42853330

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.