Evidence map›Paper›PMID 42853325›Full record

ArticleInternational urology and nephrology2026

Heterogeneous 30-day readmission risk in diabetic kidney disease: a nationwide analysis stratified by phenotype, age, and socioeconomic status.

Qimeng Zhu, Yang Ge, Tongxin Wang, Hang Dong, Menghan Liu, Zihan Xu, Panpan Yin, Jia Liu

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Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Qimeng ZhuShandong Clinical Research Center of Diabetes and Metabolic Diseases, Jinan, 250021, Shandong, China.
Yang GeShandong Clinical Research Center of Diabetes and Metabolic Diseases, Jinan, 250021, Shandong, China.
Tongxin WangShandong Clinical Research Center of Diabetes and Metabolic Diseases, Jinan, 250021, Shandong, China.
Hang DongKey Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Menghan LiuShandong Clinical Research Center of Diabetes and Metabolic Diseases, Jinan, 250021, Shandong, China.
Zihan XuShandong Clinical Research Center of Diabetes and Metabolic Diseases, Jinan, 250021, Shandong, China.
Panpan YinKey Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Jia LiuKey Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China. liujia_625@163.com.

Funding

Natural Science Foundation of Shandong Province ZR2025MS1380
6 · The paper itself

Abstract

backgroundDiabetic kidney disease (DKD) carries substantial hospital readmission burden. We characterized 30-day readmission patterns following DKD hospitalization, with stratified analyses by phenotype, age, and social determinants of health (SDOH).

methodsUsing the 2018 Nationwide Readmissions Database (NRD) with complex survey-weighted analysis, we identified adult index hospitalizations with a discharge diagnosis of DKD (ICD-10-CM E10.21, E10.22, E11.21, or E11.22) in any diagnostic position (January-November 2018). Survey-weighted multivariable logistic regression compared type 1 versus type 2 DKD, with separate models fitted within strata of age group, insurance type, and median household income quartile. Wald interaction tests assessed whether the phenotype association differed across strata.

resultsAmong 1,291,033 index hospitalizations, the 30-day all-cause readmission rate was 15.96% (95% CI 15.78%-16.14%), higher for type 1 than type 2 DKD (22.42% vs. 15.69%; p<0.001). Non-diabetes-related systemic diagnoses accounted for 91.97% of readmissions. Type 1 DKD exhibited an inverse age-readmission gradient (28.8% in patients <40 years to 15.2% in those >79 years; age × phenotype interaction p = 9.28×10⁻

conclusionsReadmission risk in DKD is heterogeneous across diabetes phenotype, age, and socioeconomic strata, driven predominantly by non-diabetes-related systemic comorbidities. Insurance type modified the phenotype-readmission association, most markedly among Medicaid-insured patients.

Indexed as

Diabetic kidney diseaseHealth disparitiesNationwide Readmissions DatabaseReadmissionSocial determinants of health

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