Evidence map›Paper›PMID 42853275›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Selecting the myopic target for an enhanced monofocal IOL in highly myopic eyes: -2.0 D versus - 3.0 D.

Danyue Chen, Haowen Lin, Xiaohang Xie, Yu Zhang, Jinhong Zhang, Xiaozhang Qiu, Xuhua Tan, Jiaqing Zhang, Lixia Luo

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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Danyue Chen *State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Haowen Lin *State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Xiaohang XieState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Yu ZhangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Jinhong ZhangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Xiaozhang QiuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Xuhua TanState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Jiaqing ZhangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China. zhangjiaqing@gzzoc.com.
Lixia LuoState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China. luolixia@mail.sysu.edu.cn.

Funding

Program for Supporting and Cultivating Outstanding Scientific and Technological Talents CXQN-008Research Funds of the State Key Laboratory of Ophthalmology 2025QNMY02
6 · The paper itself

Abstract

purposeTo determine the optimal myopic target refraction for enhanced monofocal IOL implantation in highly myopic cataract patients.

methodsA retrospective comparative study was conducted in Zhongshan Ophthalmic Center, China. Cataract patients with axial length (AL) ≥ 26 mm who underwent phacoemulsification with enhanced monofocal IOL implantation were included. Participants were divided into 2 groups by target refraction: Group 1 (-2 diopters [D]) and Group 2 (-3 D). Uncorrected distance (UDVA), intermediate (UIVA), near (UNVA) visual acuity, corrected distance visual acuity (CDVA), objective visual quality, and subjective satisfaction were evaluated 3 months postoperatively. Subgroup analyses were performed for 26 mm ≤ AL < 28 mm and AL ≥ 28 mm.

resultsA total of 94 eyes of 94 patients were analyzed. Group 1 showed superior UDVA (0.48 vs. 0.72 logMAR, P < .001), UIVA at 80 cm (0.17 vs. 0.32 logMAR, P < .001) and 60 cm (0.13 vs. 0.23 logMAR, P = .003), and higher spectacle independence at far distance (20.00% vs. 2.04%, P = .011) than Group 2. UNVA at 40 cm, CDVA, and other outcomes were similar between groups (all P > .05). Similar trends were observed across AL subgroups.

conclusionAn enhanced monofocal IOL targeted at -2.0 D provided superior UDVA and UIVA while maintaining comparable UNVA in highly myopic eyes. We recommend a target refraction of -2.0 D for eyes with AL < 28 mm, while a personalized approach is advised for eyes with AL ≥ 28 mm or for patients with shorter habitual reading distances.

Indexed as

Cataract surgeryEnhanced monofocal intraocular lensesHighly myopic eyesVisual outcomes

Identifiers

PMID42853275

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