ArticleEuropean archives of psychiatry and clinical neuroscience2026
Examining the association between autistic traits and psychopathology in the general population: are there sex differences?
Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
Abstract
introductionAutistic traits (ATs) are linked to increased vulnerability to psychopathology. While sex differences are studied in clinical autism, little is known about these associations in the general population. This study examines sex-specific associations between ATs and psychopathology in a community sample of adolescents and young adults.
methodsData from 788 participants (475 females), aged 15-35 years (mean = 17.48 ± 3.60) in the TwinssCan cohort were used. ATs were assessed using Autism Spectrum Quotient (AQ), while psychopathology and psychosis expression were measured with the Symptom Checklist-90 Revised (SCL-90) and Community Assessment of Psychic Experiences (CAPE). Sex-stratified linear regression models examined associations with SCL-90 and CAPE scores. Chow's test was used for exploratory sex comparisons.
resultsIn both sexes, total AQ scores were positively associated with the total SCL-90 score and all its subscales, as well as with total CAPE and all its subscales. No significant sex difference was found for either total SCL-90 or total CAPE. In exploratory post-hoc comparisons, a nominally statistically significant sex difference was observed for the obsessive-compulsive SCL-90 subscale (p = 0.03), where AQ accounted for 5.6% of the variance in males compared to 15.86% in females. A nominally statistically significant sex difference was found in the CAPE depressive subscale as well (p = 0.03), where AQ explained 4.78% of the variance in males versus 13.53% in females. DISCUSSION: The findings highlight that ATs relate to broad psychopathology across sexes, whereas domain-specific sex differences emerged in exploratory post-hoc comparisons. Future studies should replicate findings in clinical and longitudinal samples.
Indexed as
Identifiers
42853268What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.