Evidence map›Paper›PMID 42852424›Full record

ArticleJournal of emergencies, trauma, and shock

Is Sarcopenia Associated with Worse Postoperative Outcomes following Emergency Laparotomy? A Systematic Review and Meta-analysis.

Faisal Abdulaziz AlGhamdi, Mubarak A Alkhudair, Saud A AlShehri, Nasser Abdulsalam AlJoaib, Muhammad Talha Maniya, Anusha Abdul Muqeet Farid, Umna Aziz, Abdulaziz M Saati, Mishal A Abu Melha, Talal R Aldukhayyil and 2 more

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Article in Journal of emergencies, trauma, and shock. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Faisal Abdulaziz AlGhamdiCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Mubarak A AlkhudairCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Saud A AlShehriCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Nasser Abdulsalam AlJoaibCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Muhammad Talha ManiyaDepartment of Medicine, Ziauddin University, Karachi, Pakistan.
Anusha Abdul Muqeet FaridDepartment of Medicine, Ziauddin University, Karachi, Pakistan.
Umna AzizDepartment of Medicine, Dow International Medical College, Karachi, Pakistan.
Abdulaziz M SaatiCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Mishal A Abu MelhaCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Talal R AldukhayyilUniversity of Lancashire, Preston, United Kingdom.
Abdulaziz K AlNaimiCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Bader K AlossaimiDepartment of Emergency, King Fahad University Hospital, Khobar, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The association between sarcopenia and many postoperative outcomes is not well-established. Aims: This meta-analysis aims to clarify the potential of sarcopenia to predict these postoperative outcomes. Methods: A search of PubMed, EMBASE, and Cochrane CENTRAK databases was performed until November 2023 in accordance with Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Studies that met the inclusion criteria were extracted and their quality assessment was done using the Newcastle-Ottawa Scale. The pooled analysis was done using a random-effects model with dichotomous outcomes expressed as odds ratio (OR) and continuous as weighted mean differences with 95% confidence intervals (CIs). Results: Seventeen studies met the inclusion criteria with a total of 5879 patients, with 1690 diagnosed with sarcopenia. Sarcopenia was shown to be significantly associated with increased risk of inpatient mortality (OR = 5.18, 95% CI: 1.04-25.68; Conclusion: Our meta-analysis provided insights into sarcopenia and postoperative outcomes of emergency surgeries. We demonstrated the significant association between the presence of sarcopenia and the presentation of postoperative adverse outcomes and markers of worsened quality of recovery.

Indexed as

Emergency laparotomymeta-analysismortalitysarcopenia

Identifiers

PMID42852424
PMCPMC13649207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.