ArticleCureus2026
Repeated Thrombolysis Using Tenecteplase in a Patient With Early Recurrent Ischaemic Stroke.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ischaemic stroke is responsible for significant morbidity and mortality. Reperfusion therapy with intravenous thrombolysis is used to improve outcomes in patients with acute ischaemic stroke within 4.5 hours of symptom onset, but is generally contraindicated in early recurrent ischaemic stroke. Despite this, cases have been reported of patients who have had repeated thrombolysis using alteplase and achieved a good outcome. Tenecteplase, a variant of alteplase with higher specificity for fibrin and a longer half-life, is increasingly used as an alternative thrombolytic agent. However, there are no previously reported cases of repeated thrombolysis using tenecteplase. Here we report the first case of a 69-year-old male patient who received repeated thrombolysis with tenecteplase, rather than alteplase, in early recurrent ischaemic stroke.
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