Evidence map›Paper›PMID 42852381›Full record

ArticleProceedings of the ... Workshop on Patient-Oriented Language Processing2026

Reasoning, Contrastive, and In-Context Strategies for Opioid Use Stage Detection on Social Media.

Vinu Ekanayake, Ramakanth Kavuluru

Abstract read
In one paragraph

Article in Proceedings of the ... Workshop on Patient-Oriented Language Processing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vinu EkanayakeUniversity of Kentucky, Lexington, KY USA.
Ramakanth KavuluruUniversity of Kentucky, Lexington, KY USA.

Funding

Fast and fine: NLP methods for near real-time and fine-grained overdose surveillanceR01DA057686 · NIDA · UNIVERSITY OF KENTUCKY · PI KAVULURU, VENKATA NAGA RAMAKANTH · 2022 to 2025
$1.7M
NIDA NIH HHS R01 DA057686
6 · The paper itself

Abstract

The opioid epidemic has ravaged the US for the past two decades and is still a persistent threat. During the same time, the increasing use of social media has created a new avenue for people to share their journeys regarding opioid use. In this context, research in automatically determining opioid use stages (e.g., misuse, addiction, recovery) based on self disclosures in social media posts is gaining traction. In this paper, using a recent benchmark, we assess different supervised strategies for identifying self-disclosed opioid use stages from Reddit posts. We consider distilled reasoning traces from DeepSeek R1 (an open weights reasoning model), supervised contrastive learning (SCL), and few-shot in-context learning (ICL) with GPT-5 to conduct a variety of experiments with encoder and encoder-decoder models. We also conduct direct zero-shot (ZS) experiments with GPT 5 and GPT 5.2. Across different models and datasets, our strategies provide improvements in performance with some nuances that are too subtle to elaborate in the abstract. A surprising finding is that ZS results with GPT-5 are better than all supervised results, which ushers a new frontier for LLM-based classification of opioid use in social media posts. Our code is available for reuse and replication: https://github.com/bionlproc/Opioid-Stage.

Indexed as

contrastive learningOpioid use stagestest time reasoningzero shot learning

Identifiers

PMID42852381
PMCPMC13648211

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.