Evidence map›Paper›PMID 42852341›Full record

ArticleACS omega2026

18AA Reprograms the Pyruvate Cycle and Enhances Proton Motive Force to Potentiate Ceftazidime-Avibactam against Drug-Resistant

Jiao Xiang, Xu-Feng Li, Hao-Feng Lai, Yi-Yang Li, Zhuang-Gui Chen, Li-Fen Yang

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiao XiangChildren's Medical Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510000, China.ORCID https://orcid.org/0009-0000-1808-751X
Xu-Feng LiChildren's Medical Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510000, China.
Hao-Feng LaiChildren's Medical Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510000, China.
Yi-Yang LiChildren's Medical Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510000, China.
Zhuang-Gui ChenChildren's Medical Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510000, China.
Li-Fen YangChildren's Medical Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510000, China.ORCID https://orcid.org/0000-0002-1888-3775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rising threat of carbapenem-resistant Enterobacteriaceae demands novel strategies to restore antibiotic efficacy. Here we show that compound amino acid injection (18AA), a clinically approved parenteral nutrition formulation, markedly potentiates ceftazidime-avibactam (CZA) against multidrug-resistant and carbapenem-resistant

Identifiers

PMID42852341
PMCPMC13648092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.