Evidence map›Paper›PMID 42852336›Full record

ArticleEnvironmental health perspectives2026

Guiding Risk Reduction for Breast Cancer-Relevant Chemicals (BC-Chems): Chemical Production Volumes, Sources, Intake Levels, Emissions, and Regulations.

Jennifer E Kay, Rashmi Shakti, Jillian T McEneaney, Claudia Polsky, Megan Schwarzman, Ruthann A Rudel

Abstract read
In one paragraph

Article in Environmental health perspectives, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer E KaySilent Spring Institute, Newton, Massachusetts 02460, United States.ORCID https://orcid.org/0000-0001-5891-0689
Rashmi ShaktiSilent Spring Institute, Newton, Massachusetts 02460, United States.
Jillian T McEneaneySilent Spring Institute, Newton, Massachusetts 02460, United States.
Claudia PolskyUniversity of California, Berkeley, School of Law, Berkeley, California 94704, United States.
Megan SchwarzmanUniversity of California, Berkeley, School of Public Health, Berkeley, California 94704, United States.ORCID https://orcid.org/0000-0002-6333-1822
Ruthann A RudelSilent Spring Institute, Newton, Massachusetts 02460, United States.ORCID https://orcid.org/0000-0002-1809-4127

Funding

Quantifying early biomarkers of mammary carcinogenesis with multiplexed spatial biologyK01ES036182 · NIEHS · SILENT SPRING INSTITUTE · PI Jennifer Kay · 2024 to 2026
$469k
NIEHS NIH HHS K01 ES036182
6 · The paper itself

Abstract

Breast cancer (BC) among women in all age groups continues to increase. Changes in reproductive risk factors cannot explain these trends, and rising rates among women under 40 cannot be explained by cancer screening, suggesting other factors are involved. We recently identified 920 chemicals whose biological activity suggests they can increase BC risk, the breast cancer-relevant chemical (BC-Chem) list, because they induce mammary tumors in rodents or activate estrogen or progesterone signaling

Indexed as

Breast NeoplasmsEnvironmental ExposureFemaleHumansRisk Reduction BehaviorUnited States

Identifiers

PMID42852336
PMCPMC13648088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.