Evidence map›Paper›PMID 42852320›Full record

ArticleJournal of the Endocrine Society2026

Longer sleep duration and the incidence and progression of diabetic nephropathy: a prospective cohort study.

Fuki Ikeda, Tomoya Mita, Yusuke Osonoi, Yuki Someya, Takeshi Osonoi, Miyoko Saito, Shiho Nakayama, Hidenori Ishida, Ryota Ishii, Masahiko Gosho and 1 more

Abstract read
In one paragraph

Article in Journal of the Endocrine Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fuki IkedaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan.
Tomoya MitaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan.ORCID https://orcid.org/0000-0002-4401-2965
Yusuke OsonoiDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan.
Yuki SomeyaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan.
Takeshi OsonoiNaka Kinen Clinic, Naka City, Ibaraki 311-0113, Japan.
Miyoko SaitoNaka Kinen Clinic, Naka City, Ibaraki 311-0113, Japan.
Shiho NakayamaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan.
Hidenori IshidaNaka Kinen Clinic, Naka City, Ibaraki 311-0113, Japan.
Ryota IshiiDepartment of Biostatistics, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.
Masahiko GoshoDepartment of Biostatistics, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.
Hirotaka WatadaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan.ORCID https://orcid.org/0000-0001-5961-1816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sleep duration has been linked to adverse health outcomes, but its association with diabetic nephropathy remains unclear. Objective: This study aimed to assess the association between sleep duration and a composite endpoint of incidence and progression of diabetic nephropathy. Methods: The study participants were 678 Japanese outpatients with type 2 diabetes. Lifestyle habits were assessed at baseline and at years 2 and/or 5. Mean values of lifestyle factors were calculated by averaging measurements from baseline to the date of endpoint onset or the end of follow-up. A multivariable Cox proportional hazards model was used. Results: During a follow-up of 6.0 ± 2.7 years, 215 participants experienced the endpoint. Among lifestyle factors, mean sleep duration was the only factor associated with the endpoint. Compared with participants sleeping <6 hours, the multivariable-adjusted hazard ratios for mean sleep duration of 6 to <7, 7 to <8, and ≥8 hours were 1.08 (95% CI, 0.74-1.57), 1.56 (95% CI, 1.05-2.31), and 1.92 (95% CI, 1.15-3.19), respectively ( Conclusion: Longer, but not shorter, sleep duration is associated with an increased risk of incidence and progression of diabetic nephropathy.

Indexed as

diabetic nephropathylifestyle habitsmetabolic profilesleep

Identifiers

PMID42852320
PMCPMC13648002

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.