Evidence map›Paper›PMID 42852307›Full record

ArticleClinical case reports2026

Beyond the Oropharynx: TTMV-HPV DNA Detection in a p16-Positive Hypopharyngeal Squamous Cell Carcinoma.

Jacob Beiriger, Brayden Seliger, Silvia Soule, Hilary C McCrary, Richard B Cannon

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacob BeirigerDepartment of Otolaryngology-Head and Neck Surgery University of Utah Salt Lake City Utah USA.ORCID https://orcid.org/0000-0001-8552-787X
Brayden SeligerDepartment of Otolaryngology-Head and Neck Surgery University of Utah Salt Lake City Utah USA.
Silvia SouleDepartment of Otolaryngology-Head and Neck Surgery University of Utah Salt Lake City Utah USA.ORCID https://orcid.org/0000-0001-8942-7016
Hilary C McCraryDepartment of Otolaryngology-Head and Neck Surgery University of Utah Salt Lake City Utah USA.ORCID https://orcid.org/0000-0002-9523-0727
Richard B CannonDepartment of Otolaryngology-Head and Neck Surgery University of Utah Salt Lake City Utah USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma TTMV-HPV16 DNA provided complementary molecular evidence in a p16-positive hypopharyngeal squamous cell carcinoma, while PET/CT localized the occult left pyriform sinus primary. Serial postoperative TTMV-HPV DNA assays remained undetectable through approximately 19 months of clinical and radiographic surveillance.

Indexed as

circulating tumor DNAp16‐positive hypopharyngeal cancerpyriform sinus carcinomatransoral robotic surgeryTTMV‐HPV DNA

Identifiers

PMID42852307
PMCPMC13648016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.