ArticleACS omega2026
Demystifying Experimental Parameters in Optical Photothermal Imaging in Aqueous Media.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
5 authors.
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Abstract
Optical photothermal infrared (O-PTIR) spectroscopy is an indirect mid-infrared spectral imaging technique that enables label-free chemical analysis with submicrometer resolution. The technique is often used for analyzing cells and tissues and is discussed as capable of measuring in aqueous media, yet a quantitative understanding of its signal formation in liquids remains incomplete. Here, we present a systematic experimental study of transmission-mode O-PTIR supported by detailed simulations on the underlying signal generating process, focusing on O-PTIR applied to a water filled cuvette comprising two CaF
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