ArticleOxford open neuroscience2026
An operant-based touchscreen morph discrimination task does not detect age-related mnemonic similarity deficits in rats.
Article in Oxford open neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
The Mnemonic Similarity Task (MST) is sensitive to age-related cognitive decline in humans and has been adapted for rodents using 3D objects, where aged animals show deficits discriminating similar lures. To improve translational alignment and increase automation, we developed a touchscreen-based rat analog using a morphed Object-Cued Spatial Choice task with 2D image stimuli. Young and aged male and female Fischer 344 × Brown Norway rats were trained in Bussey-Saksida touchscreen chambers and tested with image pairs that varied parametrically in feature overlap. In a subset of animals, we also assessed perirhinal cortical engagement using
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