Evidence map›Paper›PMID 42851947›Full record

ArticleACS omega2026

Synthesis and Cytocompatibility of Bacterial Nanocellulose-Hydroxyapatite Biocomposites with Mg, Cu, Zn, and Sr Substitution.

Michele C Formolo, Bruna Segat, Sandro R K Junior, Karina Cesca, Andrea L Dos S Schneider, Ana P T Pezzin, Luismar M Porto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michele C FormoloDepartment of Chemical Engineering, University of the Joinville Region, Joinville 89219-710, Brazil.ORCID https://orcid.org/0000-0002-6899-1264
Bruna SegatDepartment of Chemical Engineering, University of the Joinville Region, Joinville 89219-710, Brazil.ORCID https://orcid.org/0000-0001-8998-1850
Sandro R K JuniorPostgraduate Program in Health and Environment, University of the Joinville Region, Joinville 89219-710, Brazil.
Karina CescaProgram in Food Engineering, Federal University of Santa Catarina, Florianópolis 88040-900, Brazil.
Andrea L Dos S SchneiderDepartment of Chemical Engineering, University of the Joinville Region, Joinville 89219-710, Brazil.
Ana P T PezzinPostgraduate Program in Process Engineering, University of the Joinville Region, Joinville 89219-710, Brazil.
Luismar M PortoPostgraduate Program in Chemical Engineering, Federal University of Santa Catarina, Florianópolis 88040-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial nanocellulose (BNC) combined with hydroxyapatite (HAp) forms biocomposites that exhibit biomimetic properties favorable for bone regeneration. Moreover, incorporating trace elements naturally present in bone, such as Mg, Cu, Zn, and Sr, has been reported to enhance osteogenic activity and support vascularization. Despite these advantages, BNC's resistance to enzymatic degradation in vivo remains a critical limitation. To address this, BNC-based biocomposites containing cation-substituted hydroxyapatite (at varying concentrations of Mg

Identifiers

PMID42851947
PMCPMC13647905

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.