Evidence map›Paper›PMID 42851936›Full record

ArticleWorld journal of otorhinolaryngology - head and neck surgery2026

Characterization of the Middle Ear Microbiome in Meniere's Disease by 16S rRNA Gene Sequencing Compared to Chronic Suppurative Otitis Media.

Yu-Ting Tao, Lin Wang, Hong-Wei Zheng, Li-Sheng Yu

Abstract read
In one paragraph

Article in World journal of otorhinolaryngology - head and neck surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu-Ting TaoDepartment of Otolaryngology - Head and Neck Surgery People's Hospital of Peking University Beijing China.ORCID https://orcid.org/0000-0002-2714-9150
Lin WangDepartment of Otolaryngology - Head and Neck Surgery People's Hospital of Peking University Beijing China.
Hong-Wei ZhengDepartment of Otolaryngology - Head and Neck Surgery People's Hospital of Peking University Beijing China.
Li-Sheng YuDepartment of Otolaryngology - Head and Neck Surgery People's Hospital of Peking University Beijing China.ORCID https://orcid.org/0000-0001-6845-5392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the middle ear microbiome in Meniere's disease (MD) patients. Methods: Middle ear smears from 10 MD patients (ME group) and 10 chronic suppurative otitis patients (OE group) were collected during surgery and processed via 16S rRNA gene sequencing. Results: The ME group demonstrated significant differences in alpha diversity (Shannon/Simpson index, Conclusion: These findings suggested that inner ear inflammation resulted from middle ear dysbiosis may contribute to MD pathogenesis, offering novel perspectives for MD etiology and therapies.

Indexed as

16S rRNA Sequencingdysbiosismeniere's diseasemicrobiomemiddle ear

Identifiers

PMID42851936
PMCPMC13646734

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.