ArticleACS omega2026
Salt-Assisted High-Hydrostatic-Pressure Strategy to Achieve High-Efficiency Nondestructive Bacterial Inactivation for Liquid Collagen.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
Collagen and its derivatives stand out as valuable biomaterials for applications in foods, cosmetics, healthcare products, medical equipment, and drug delivery carriers due to their high biocompatibility, biodegradability, and lack of toxicity and immunogenicity. However, the problem of microbial contamination in collagen is too important to ignore, which limits its further application in various fields. Traditional bacterial inactivation methods such as heating and irradiation can effectively kill microorganisms in solid collagen, yet struggle to eliminate microbes in liquid collagen while preserving its biological activity. How to completely eradicate microorganisms in liquid collagen without loss of collagen bioactivity, namely, nondestructive bacterial inactivation, has become a key scientific challenge in the field of biomaterials. To answer this challenge, this study attempts to develop a bacterial inactivation strategy based on high hydrostatic pressure (HHP) technology to achieve nondestructive bacterial inactivation of
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Registered trials
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