Evidence map›Paper›PMID 42851820›Full record

ArticleBioengineering & translational medicine2026

Endovascular magnetic filters for removing excess chemotherapeutic drugs from blood flow using dimensionless scaling laws.

Won-Seok Heo, Steven W Hetts, Vitaliy L Rayz

Abstract read
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Article in Bioengineering & translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Won-Seok HeoSchool of Mechanical Engineering Purdue University West Lafayette Indiana USA.ORCID https://orcid.org/0000-0001-7015-111X
Steven W HettsDepartment of Radiology and Biomedical Imaging University of California San Francisco California USA.
Vitaliy L RayzSchool of Mechanical Engineering Purdue University West Lafayette Indiana USA.

Funding

Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce ToxicityR01CA194533 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM · 2015 to 2019
$2.6M
NCI NIH HHS R01 CA194533
6 · The paper itself

Abstract

Intra-arterial chemotherapy (IAC) for hepatocellular carcinoma (HCC) is limited by the escape of chemotherapeutic agents into systemic circulation, causing severe side effects such as heart failure. This study aims to develop and optimize endovascular magnetic filtration devices to enhance IAC efficacy, by targeted removal of excess drug-coated ultrasmall superparamagnetic iron oxide (USPIO) particles from circulation. Device performance was evaluated through multi-physics simulations that coupled the transport of drug-coated magnetic particles in blood flow with magnetic interactions and magnetophoretic forces. A dimensional analysis framework was applied to characterize particle capture efficiency (

Indexed as

dimensional analysishemodynamicsintra‐arterial chemotherapymagnetophoresis

Identifiers

PMID42851820
PMCPMC13646516

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.