Evidence map›Paper›PMID 42851803›Full record

ArticleFrontiers in stroke2026

Sex differences in risk factors, stroke etiology, treatment characteristics, and outcomes after endovascular treatment for anterior circulation ischemic stroke.

Marieta Peycheva, Charlotte Berger, Marino Costa, Lee Siegenthaler, Fiona Huber, Ismaël Rizzo, Marina Krasteva, Morin Beyeler, Tatiana Bremova-Ertl, Nedelina Slavova and 7 more

Abstract read
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In one paragraph

Article in Frontiers in stroke, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Marieta PeychevaDepartment of Neurology, University Hospital "Saint George", Medical University Plovdiv, Plovdiv, Bulgaria.
Charlotte BergerDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Marino CostaDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Lee SiegenthalerDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Fiona HuberDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Ismaël RizzoDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Marina KrastevaDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Morin BeyelerDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Tatiana Bremova-ErtlDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Nedelina SlavovaDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Pasquale MordasiniDepartment of Neuroradiologie, Kantonsspital Aarau, Aarau, Switzerland.
Roza M UmarovaDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Philipp BückeDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Kateryna AntonenkoDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Angelika HoffmannInstitute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Sara Pilgram-PastorDepartment of Neuroradiologie, Kantonsspital Aarau, Aarau, Switzerland.
Mirjam R HeldnerDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Sex-specific differences in vascular risk factors, stroke etiology, and outcomes after endovascular treatment (EVT) remain uncertain. We investigated these differences in a contemporary single-center cohort. Methods: Consecutive patients with acute anterior circulation ischemic stroke undergoing EVT (with-/out intravenous thrombolysis) between February 2015 and March 2023 were included. Sex differences in risk factors, treatment, successful reperfusion, and 3-month outcomes (mRS ≤ 1, ≤ 2, and mortality) were examined; multivariable models included interactions with age, stroke etiology, and bridging therapy. Results: Among 1,764 patients (median age 76 years, 48% women), women were older (79.4 vs. 73.3 years, Conclusion: Women and men differ in risk profiles, stroke mechanisms, and unadjusted outcomes after EVT. However, sex was not independently associated with outcomes overall, although age may modify its association with favorable functional outcome.

Indexed as

acute ischemic strokeanterior circulationendovascular treatmentsex-specific differencesstroke outcomes

Identifiers

PMID42851803
PMCPMC13647262

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.