Evidence map›Paper›PMID 42851757›Full record

ArticleReproductive medicine and biology

Cabergoline Suppresses FSH-Induced Differentiation and Steroidogenesis in Primary Cultured Rat Granulosa Cells.

Yusuke Mori, Hiroshi Kishi, Ayako Hasunuma, Yuta Kasahara, Aikou Okamoto

Abstract read
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yusuke MoriDepartment of Obstetrics and Gynecology The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0009-0001-3333-001X
Hiroshi KishiDepartment of Obstetrics and Gynecology The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0003-1562-410X
Ayako HasunumaDepartment of Obstetrics and Gynecology The Jikei University School of Medicine Tokyo Japan.
Yuta KasaharaDepartment of Obstetrics and Gynecology The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-6369-1086
Aikou OkamotoDepartment of Obstetrics and Gynecology The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-5079-0464

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Cabergoline, a dopamine D Methods: Primary granulosa cells were isolated from immature female rats pretreated with diethylstilbestrol (DES) and cultured under four conditions: control, cabergoline alone, FSH alone, and FSH combined with cabergoline. mRNA expression of Results: Cabergoline significantly suppressed FSH-induced mRNA expression of Conclusions: Cabergoline suppresses FSH-induced granulosa cell differentiation and steroidogenesis, at least partly through attenuation of FSH-induced cAMP signaling. Although dopamine D

Indexed as

cabergolinefollicle‐stimulating hormonegranulosa cellsluteinizing hormone receptorssteroidogenesis

Identifiers

PMID42851757
PMCPMC13647201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.