ArticleFrontiers in oncology2026
Ameloblastic carcinoma with isolated supramandibular lymph node metastasis in an adolescent: a case report and review of the literature.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To report a rare case of maxillary ameloblastic carcinoma (AC) with buccofacial lymph node metastasis in a 17-year-old male patient, describe its clinical, radiological, and pathological progression, and provide clinical references for routine patient management. Case description: The patient presented to our hospital with suspected recurrent peripheral ameloblastoma (PA). Cone-beam computed tomography (CBCT) revealed an osteolytic lesion in the right maxilla. Intraoperative frozen section pathology confirmed the diagnosis of ameloblastoma, extended tumorectomy, segmental maxillectomy, and submental island flap reconstruction were conducted. Histopathological examination confirmed the diagnosis of AC. Eight months after segmental maxillectomy, a soft tissue mass overlying the right mandibular buccal region rapidly enlarged. Contrast-enhanced CT revealed heterogeneous enhancement of the lesion with internal necrotic components. Intraoperative pathological examination suggested a malignant tumor. The patient subsequently underwent reoperation: extended resection of the right buccal mass, right suprahyoid lymphadenectomy, and right cervical lymph node dissection. Postoperative pathological examination confirmed AC with supramandibular lymph node metastasis. Following lymph node dissection, the patient received radiotherapy and chemotherapy for two months. At the 6-month follow-up, imaging and clinical examinations revealed no evidence of tumor recurrence or distant metastatic lesions. The patient is currently under regular long-term surveillance to monitor disease progression. Conclusion: This study reports a case of maxillary AC with isolated supramandibular lymph node metastasis. To our knowledge, this represents the first documented case. Clinicians should be alert to occult buccofacial lymph node metastasis in patients with AC invading the buccal soft tissues, and multimodal imaging is recommended for complete preoperative tumor staging. Individualized combined buccofacial and cervical lymph node dissection may improve locoregional control in patients complicated with buccofacial lymph node metastasis. This study can provide a reference for the identification of rare metastatic patterns and individualized diagnosis and treatment of AC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.