Evidence map›Paper›PMID 42851430›Full record

ArticleFrontiers in immunology2026

Case Report: Unplanned pregnancy during treatment with inebilizumab in patients with AQP4-IgG-seropositive NMOSD: report of two cases.

Wenqin Luo, Fenglin Shi, Zhu Xu, Yunli Yu, Dian He

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenqin Luo *Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Fenglin Shi *Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Zhu XuDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Yunli YuDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Dian HeDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) predominantly affects women and has a median age at onset of 40 years, meaning that many patients are of childbearing age. However, management of pregnant women with NMOSD remains extremely challenging. We report two patients with NMOSD who had unplanned pregnancies during inebilizumab (INE) treatment and successful deliveries. These cases provide preliminary clinical information regarding maternal disease control and pregnancy outcomes following INE exposure.

Indexed as

Antibodies, Monoclonal, HumanizedAquaporin 4Immunoglobulin GNeuromyelitis OpticaPregnancy, UnplannedAdultAutoantibodiesFemaleHumansPregnancyPregnancy OutcomeTreatment OutcomeAntibodies, Monoclonal, HumanizedAQP4 protein, humanAquaporin 4AutoantibodiesImmunoglobulin GinebilizumabB-cell depletioncase reportinebilizumabneuromyelitis optica spectrum disorderpregnancy

Identifiers

PMID42851430
PMCPMC13646095

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.