ArticleFrontiers in medicine2026
Association between triglyceride glucose-body mass index and diabetic kidney disease in hospitalized patients with type 2 diabetes mellitus: a retrospective cross-sectional study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To analyze the association between the triglyceride glucose-body mass index (TyG-BMI) and diabetic kidney disease (DKD) in patients with type 2 Diabetes Mellitus (T2DM). Methods: A single-center retrospective cross-sectional study was conducted enrolling 1,966 patients diagnosed with T2DM. General clinical data, as well as data on medication use, smoking history, alcohol consumption, and comorbidities, were collected. According to DKD diagnostic criteria, participants were divided into the non-DKD group ( Results: Compared to the Non-DKD group, patients in the DKD group exhibited significantly higher age, DM duration, SBP, DBP, WC, WHR, BMI, sCr, UACR, FPG, 2hPPG, HbA1c, FCP, TG, and the TyG-BMI index ( Conclusion: This study identified a significant association between the TyG-BMI index and DKD in patients with T2DM, with a dose-response trend. As a simple composite index derived from TG, FBG, and BMI, TyG-BMI index may serve as an auxiliary reference indicator for DKD risk assessment in T2DM patients, facilitating the identification of high-risk individuals. However, due to the selection bias inherent in the hospitalized population and the cross-sectional design, these findings require further validation in community-based cohorts.
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