ArticleChonnam medical journal2026
Age-Dependent Benefit of ECPR in OHCA: An Interaction Analysis.
Article in Chonnam medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
ECPR effectiveness in OHCA remains inconsistent, and age-related effect modification is not well defined. This retrospective study analyzed 470 adult patients (2011-2025), comparing ECPR (n=71) to CCPR (n=399). Using multivariable regression and inverse probability of treatment weighting (IPTW), we found that increasing age independently associated with higher mortality (aOR: 1.064). Also, a significant interaction between age and treatment strategy was identified (p<0.001). ECPR provided a substantial mortality reduction in younger patients, but this benefit progressively attenuated with age. These findings demonstrate that ECPR effectiveness is strongly age-dependent. Consequently, age should be considered as a continuous effect modifier rather than a rigid eligibility threshold for ECPR selection.
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