Evidence map›Paper›PMID 42851018›Full record

ReviewMicrobial biotechnology2026

Metabolic Design Patterns for a Regenerative Architecture.

Rachel Armstrong, Pablo Carbonell, Deshendran Moodley, Ioannis Ieropoulos, Jorge Barriuso

Abstract readReview
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In one paragraph

Review in Microbial biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel ArmstrongDepartment of Architecture, Faculty of Architecture, KU Leuven, Ghent/Brussels, Belgium.ORCID https://orcid.org/0000-0002-3516-6815
Pablo CarbonellInstitute for Integrative Systems Biology (I2SysBio), CSIC-UV, Paterna, Valencia, Spain.ORCID https://orcid.org/0000-0002-0993-5625
Deshendran MoodleyArtificial Intelligence Research Unit (AIRU), Centre for Artificial Intelligence Research, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-4340-9178
Ioannis IeropoulosDepartment of Civil, Maritime and Environmental Engineering, University of Southampton, Southampton, UK.ORCID https://orcid.org/0000-0002-9641-5504
Jorge BarriusoDepartment of Biotechnology, Center for Biological Research Margarita Salas, Spanish National Research Council (CIB-CSIC), Madrid, Spain.ORCID https://orcid.org/0000-0003-0916-6560

Funding

HORIZON EUROPE European Innovation Council 101114746
6 · The paper itself

Abstract

The contemporary home remains trapped in a mechanistic paradigm of twentieth-century resource consumption, where metabolic biological presence is considered irrelevant to the functioning of a building. Presenting the home as a conceptual vehicle for metabolically optimised living spaces in dense urban environments, this paper develops a conceptual framework of metabolic design patterns that enables the staged retrofit of bioreactors, from composters and fermenters to bioelectrical systems, into human-occupied living spaces. By bringing circular resource processing into the heart of domestic life the principles for regenerative homes are established. Bioelectrical systems are given particular attention because they provide real-time, connectable data through electricity as a medium for information, power, and chemical transformation simultaneously, forming a connective backbone for generating the metabolic design patterns. Three patterns are developed: Toilet as Hearth, Kitchen Garden, and Greywater Wetland, each integrating bioelectrical systems into the habitation programme to provide the respective architectural affordances. The framework proposes a staged retrofit pathway to implementation from passive sensing to neighbourhood metabolic exchange, supported by a conceptual anatomical atlas for diagnosing metabolic failures in established metabolic systems. This revaluation positions metabolic presence as a generative resource rather than a cost, directly addressing SDGs 6, 7, 9, 11 and 12.

Indexed as

ArchitectureBioelectric Energy SourcesBioreactorsHumans12‐V DC infrastructurebioelectrical systemscircular economyliving architecturemetabolic design patternsmeta holobiontmicrobial fuel cells

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.