Evidence map›Paper›PMID 42850404›Full record

ArticlePrevention science : the official journal of the Society for Prevention Research2026

Developmental Trajectories of Alcohol, Mental Health and Physical Health among American Indian and First Nation Adolescents: Understanding the Role of Land-Based Cultural Engagement, Family, and Peers.

Helen Russette, Anthony Rodriguez, Chelsea Wesner, Tina Handeland, Elizabeth J D'Amico, Faith Price, Fiona Grubin, Kelly Sittner, Melissa Walls

Abstract read
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In one paragraph

Article in Prevention science : the official journal of the Society for Prevention Research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Helen RussetteCenter for Indigenous Health, Johns Hopkins University, 415 N. Washington Street, Baltimore, MD, 21231, USA. hrusset1@jhu.edu.ORCID http://orcid.org/0000-0002-6144-2385
Anthony RodriguezRAND, 20 Park Plaza, Suite 910, Boston, MA, 02116, USA.
Chelsea WesnerCenters for American Indian and Alaska Native Health, University of Colorado Anschutz, Auora, CO, USA.
Tina HandelandCenter for Indigenous Health, Johns Hopkins University, 415 N. Washington Street, Baltimore, MD, 21231, USA.
Elizabeth J D'AmicoRAND, 1776 Main St., Santa Monica, CA, 90407, USA.
Faith PriceCenter for Indigenous Health, Johns Hopkins University, 415 N. Washington Street, Baltimore, MD, 21231, USA.
Fiona GrubinCenter for Indigenous Health, Johns Hopkins University, 415 N. Washington Street, Baltimore, MD, 21231, USA.
Kelly SittnerDepartment of Sociology, Oklahoma State University, Stillwater, OK, USA.
Melissa WallsCenter for Indigenous Health, Johns Hopkins University, 415 N. Washington Street, Baltimore, MD, 21231, USA.

Funding

Towards understanding the influence of greenspace and blue-space exposure mediated by culture-based human-nature interaction on onset of substance use among Indigenous youth.R01DA039912 · NIDA · UNIVERSITY OF MINNESOTA · PI SITTNER, KELLEY, WALLS, MELISSA L. · 2016 to 2025
$6.4M
Applying the Traditional Ecological Knowledge framework to develop and evaluate a nature-based culturally grounded substance misuse intervention for Native American families.K01DA060294 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Helen Russette · 2024 to 2026
$547k
NIDA NIH HHS K01DA060294NIDA NIH HHS R01DA039912NIMH NIH HHS 2R25MH084565-11
6 · The paper itself

Abstract

We applied the Indigenous Traditional Ecological Knowledge (ITEK) framework to understand patterns of wellbeing among American Indian and First Nation (AI/FN) adolescents; risks and protective factors associated with alcohol use, mental health, and physical health that can be translated into prevention intervention strategies. Latent profile analysis and growth mixture modeling (GMM) were applied to identify and examine patterns of change among distinct subgroups of AI/FN youth (Wave 1 N = 735, M age = 11.09, 50.2% female) residing on or near a Tribal Nation or Reserve on the role of land-based cultural activity participation, family warmth and support, and having risk-taking peers at baseline. GMM explored how risk and protective factors were related to trajectories of alcohol use, mental health symptoms, and physical health across five waves. Four trajectory groups were identified: (1) Prosocial, low cultural engagement (62%); (2) High-risk profile (11%); (3) Risk-taking peers, mixed engagement (21%); and (4) Prosocial, high cultural and family engagement (5%). Having more risk-taking peers increased risk for alcohol use, symptoms of depression and anxiety, and lower physical health. High land-based cultural activity participation with high family warmth and support decreased risk for alcohol use and mental health indicators and lower physical health with trajectories staying below other subgroups or stable across adolescence. The ITEK framework aided in understanding critical factors for AI/FN wellbeing. Land-based healing efforts hold promise in preventing substance use and negative affect and promoting overall wellbeing among AI/FN adolescents.

Indexed as

American IndiansFirst NationsHolistic wellnessIndigenous research methodologiesMental healthPreventionSubstance useYouth

Identifiers

PMID42850404

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.